Evidence map›Paper›PMID 32971968›Full record

ReviewJournal of functional biomaterials2020

Bio-Based Electrospun Fibers for Wound Healing.

Bahareh Azimi, Homa Maleki, Lorenzo Zavagna, Jose Gustavo De la Ossa, Stefano Linari, Andrea Lazzeri, Serena Danti

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Article
  2. Multifunctional Electrospun PCL/Starch/n-AlInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
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  7. Article
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  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bahareh AzimiInteruniversity National Consortium of Materials Science and Technology (INSTM), 50121 Florence, Italy.
Homa MalekiDepartment of Carpet, University of Birjand, Birjand 9717434765, Iran.
Lorenzo ZavagnaInteruniversity National Consortium of Materials Science and Technology (INSTM), 50121 Florence, Italy.ORCID 0000-0003-2900-2694
Jose Gustavo De la OssaDoctoral School in Life Sciences, University of Siena, 53100 Siena, Italy.
Stefano LinariLinari Engineering s.r.l., 56121 Pisa, Italy.
Andrea LazzeriInteruniversity National Consortium of Materials Science and Technology (INSTM), 50121 Florence, Italy.ORCID 0000-0002-9463-1502
Serena DantiInteruniversity National Consortium of Materials Science and Technology (INSTM), 50121 Florence, Italy.ORCID 0000-0002-8155-8537

Funding

Bio-Based Industries Joint Undertaking (BBI JU) - European Union's Horizon 2020 POLYBIOSKIN G.A. 7N5839
6 · The paper itself

Abstract

Being designated to protect other tissues, skin is the first and largest human body organ to be injured and for this reason, it is accredited with a high capacity for self-repairing. However, in the case of profound lesions or large surface loss, the natural wound healing process may be ineffective or insufficient, leading to detrimental and painful conditions that require repair adjuvants and tissue substitutes. In addition to the conventional wound care options, biodegradable polymers, both synthetic and biologic origin, are gaining increased importance for their high biocompatibility, biodegradation, and bioactive properties, such as antimicrobial, immunomodulatory, cell proliferative, and angiogenic. To create a microenvironment suitable for the healing process, a key property is the ability of a polymer to be spun into submicrometric fibers (e.g., via electrospinning), since they mimic the fibrous extracellular matrix and can support neo- tissue growth. A number of biodegradable polymers used in the biomedical sector comply with the definition of bio-based polymers (known also as biopolymers), which are recently being used in other industrial sectors for reducing the material and energy impact on the environment, as they are derived from renewable biological resources. In this review, after a description of the fundamental concepts of wound healing, with emphasis on advanced wound dressings, the recent developments of bio-based natural and synthetic electrospun structures for efficient wound healing applications are highlighted and discussed. This review aims to improve awareness on the use of bio-based polymers in medical devices.

Indexed as

biodegradablebiopolymersnanofiberskintissue engineeringwound dressing

Identifiers

PMID32971968
PMCPMC7563280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.