Evidence map›Paper›PMID 32971939›Full record

ArticleToxics2020

In Vitro and In Vivo Evaluation of the Toxic Effects of Dodecylguanidine Hydrochloride.

Yeon-Mi Lim, Haewon Kim, Seong Kwang Lim, Jean Yoo, Ji-Young Lee, Ig-Chun Eom, Byung-Il Yoon, Pilje Kim, Seung-Do Yu, Ilseob Shim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yeon-Mi LimEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.ORCID 0000-0002-7431-9685
Haewon KimEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Seong Kwang LimEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Jean YooEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Ji-Young LeeEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Ig-Chun EomEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Byung-Il YoonCollege of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Pilje KimEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Seung-Do YuEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.
Ilseob ShimEnvironmental Health Research Department, National Institute of Environmental Research, Incheon 22689, Korea.ORCID 0000-0003-4010-4886
National Institute of Environmental Research · KRKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxicity profiles of the widely used guanidine-based chemicals have not been fully elucidated. Herein, we evaluated the in vitro and in vivo toxicity of eight guanidine-based chemicals, focusing on inhalation toxicity. Among the eight chemicals, dodecylguanidine hydrochloride (DGH) was found to be the most cytotoxic (IC

Indexed as

bronchoalveolar lavagedodecylguanidine hydrochlorideguanidine-based chemicalsinflammationinhalation toxicity

Identifiers

PMID32971939
PMCPMC7560342
OpenAlexW3088624808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.