ReviewPathogens (Basel, Switzerland)2020
Orthohantaviruses, Emerging Zoonotic Pathogens.
Review in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 42 citations in OpenAlex.
- Design and in silico evaluation of PV-GNProtecta: an mRNA multi-epitope vaccine candidate against Puumala virus using immunoinformatics and structural analysis.Genomics & informatics · 2026Article
- Maintenance of Hokkaido virus, a genotype ofJournal of virology · 2026Article
- Purifying selection constrains the evolution of Juquitiba virus in wild Oligoryzomys nigripes communities.PLoS pathogens · 2026Article
- Characterization of minigenome systems for Hantaan and Seoul hantaviruses.Virus research · 2026Article
- Phylogenetic diversity and molecular evolution of Hantaan virus harbored by Apodemus chejuensis on Jeju Island, Republic of Korea, 2022-2023.PLoS neglected tropical diseases · 2025Article
- Recovering ImmunogenicVaccines · 2025Article
- Discovery and genomic characterization of Ulleung virus harbored by Crocidura utsuryoensis on Ulleung Island in Republic of Korea.Scientific reports · 2025Article
- Review
- Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology.Frontiers in immunology · 2025Review
- Predictors of Severity in Hemorrhagic Fever with Renal Syndrome.International journal of general medicine · 2025Article
- The discovery of novel variants reveals the genetic diversity and potential origin of Seoul orthohantavirus.PLoS neglected tropical diseases · 2024Article
- Evaluating climate-dependent distribution of orthohantaviruses with monitoring wild rodents: One Health PerspectiveBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Article
- Great genetic diversity of vector-borne bacteria and protozoan in wild rodents from Guangxi, China.PLoS neglected tropical diseases · 2024Article
- ZoonoticViruses · 2023Review
- A Development of Rapid Whole-Genome Sequencing ofViruses · 2023Article
- Evolutionary Formation and Distribution of Puumala Virus Genome Variants, Russia.Emerging infectious diseases · 2023Article
- Serological evidence of hantavirus infection in neotropical bats in an urban area of São Paulo State, Brazil.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2023Article
- Occurrence ofMicroorganisms · 2022Article
- Diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restriction.PLoS neglected tropical diseases · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 4 countries.
Funding
Abstract
Orthohantaviruses give rise to the emerging infections such as of hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) in Eurasia and the Americas, respectively. In this review we will provide a comprehensive analysis of orthohantaviruses distribution and circulation in Eurasia and address the genetic diversity and evolution of Puumala orthohantavirus (PUUV), which causes HFRS in this region. Current data indicate that the geographical location and migration of the natural hosts can lead to the orthohantaviruses genetic diversity as the rodents adapt to the new environmental conditions. The data shows that a high level of diversity characterizes the genome of orthohantaviruses, and the PUUV genome is the most divergent. The reasons for the high genome diversity are mainly caused by point mutations and reassortment, which occur in the genome segments. However, it still remains unclear whether this diversity is linked to the disease's severity. We anticipate that the information provided in this review will be useful for optimizing and developing preventive strategies of HFRS, an emerging zoonosis with potentially very high mortality rates.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.