Evidence map›Paper›PMID 32971886›Full record

ReviewMolecules (Basel, Switzerland)2020

The Lipidome Fingerprint of Longevity.

Mariona Jové, Natàlia Mota-Martorell, Irene Pradas, José Daniel Galo-Licona, Meritxell Martín-Gari, Èlia Obis, Joaquim Sol, Reinald Pamplona

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The lipidomes ofAging · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariona JovéDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.
Natàlia Mota-MartorellDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.
Irene PradasDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.
José Daniel Galo-LiconaDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.
Meritxell Martín-GariDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.ORCID 0000-0003-0539-7775
Èlia ObisDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.
Joaquim SolDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.
Reinald PamplonaDepartment of Experimental Medicine, Lleida University (UdL), Lleida Biomedical Research Institute (IRBLleida), 25198 Lleida, Spain.ORCID 0000-0003-4337-6107

Funding

Departament de Salut, Generalitat de Catalunya SLT002/16/00250Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya 2017SGR696Ministerio de Ciencia, Innovación y Universidades RTI2018-099200-BI00
6 · The paper itself

Abstract

Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies and genetics and nutritional interventions in invertebrates, vertebrates, and exceptionally long-lived animal species-humans included-demonstrate that both the cell membrane fatty acid profile and lipidome are a species-specific optimized evolutionary adaptation and traits associated with longevity. All these emerging observations point to lipids as a key target to study the molecular mechanisms underlying differences in longevity and suggest the existence of a lipidome profile of long life.

Indexed as

Lipid MetabolismLongevityAnimalsCell MembraneHumansfatty acidslipidomicslongevitymembrane unsaturationperoxidation index

Identifiers

PMID32971886
PMCPMC7570520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.