Evidence map›Paper›PMID 32971830›Full record

ArticleJournal of clinical medicine2020

Evaluation of an Amino Acid Mix on the Secretion of Gastrointestinal Peptides, Glucometabolic Homeostasis, and Appetite in Obese Adolescents Administered with a Fixed-Dose or ad Libitum Meal.

Antonello E Rigamonti, Sofia Tamini, Sabrina Cicolini, Alessandra De Col, Diana Caroli, Stefania Mai, Eugenia Rondinelli, Antonella Saezza, Silvano G Cella, Alessandro Sartorio

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Nutrient Combinations Sensed by L-Cell Receptors Potentiate GLP-1 Secretion.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonello E RigamontiDepartment of Clinical Sciences and Community Health, University of Milan, 20129 Milan, Italy.ORCID 0000-0002-2489-9108
Sofia TaminiExperimental Laboratory for Auxo-endocrinological Research, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.ORCID 0000-0002-2503-5117
Sabrina CicoliniExperimental Laboratory for Auxo-endocrinological Research, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.ORCID 0000-0003-1795-7848
Alessandra De ColExperimental Laboratory for Auxo-endocrinological Research, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.
Diana CaroliExperimental Laboratory for Auxo-endocrinological Research, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.
Stefania MaiExperimental Laboratory of Metabolic Research, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.
Eugenia RondinelliLaboratory of Clinical Analyses, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.
Antonella SaezzaDivision of Auxology, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.
Silvano G CellaDepartment of Clinical Sciences and Community Health, University of Milan, 20129 Milan, Italy.
Alessandro SartorioExperimental Laboratory for Auxo-endocrinological Research, Istituto Auxologico Italiano, IRCCS, 28824 Verbania, Italy.ORCID 0000-0002-9620-4133
IRCCS Istituto Auxologico Italiano · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins have been demonstrated to reduce food intake in animals and humans via peripheral and central mechanisms. Supplementation of a dietetic regimen with single or mixed amino acids might represent an approach to improve the effectiveness of any body weight reduction program in obese subjects. The aim of the present study was to evaluate the effects of an amino acid mix (L-arginine + L-leucine + L-glutamine + L-tryptophan) on the secretion of some gastrointestinal peptides (i.e., ghrelin and glucagon-like peptide type 1, GLP-1), glucometabolic homeostasis (i.e., glucose, insulin, and glucagon), and appetite (hunger/satiety scored by visual analogue scale, VAS) in obese adolescents (

Indexed as

amino acidsappetitegastrointestinal peptidesobesity

Identifiers

PMID32971830
PMCPMC7564111
OpenAlexW3088155732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.