Evidence map›Paper›PMID 32971756›Full record

ArticleInternational journal of environmental research and public health2020

Chest CT Computerized Aided Quantification of PNEUMONIA Lesions in COVID-19 Infection: A Comparison among Three Commercial Software.

Roberto Grassi, Salvatore Cappabianca, Fabrizio Urraro, Beatrice Feragalli, Alessandro Montanelli, Gianluigi Patelli, Vincenza Granata, Giuliana Giacobbe, Gaetano Maria Russo, Assunta Grillo and 10 more

Abstract readComparative Study
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Artificial intelligence algorithms based approach in evaluating COVID-19 patients and management.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
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  14. Immunotherapy Assessment: A New Paradigm for Radiologists.Diagnostics (Basel, Switzerland) · 2023
    Review
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  16. Review
  17. Article
  18. Article
  19. Review
  20. AI for COVID-19 Detection from Radiographs: Incisive Analysis of State of the Art Techniques, Key Challenges and Future Directions.Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Roberto GrassiDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Salvatore CappabiancaDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Fabrizio UrraroDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Beatrice FeragalliDepartment of Medical, Oral and Biotechnological Sciences-Radiology Unit "G. D'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Alessandro MontanelliLaboratory Medicine Unit, ASST Bergamo Est, 24068 Seriate, Italy.
Gianluigi PatelliDepartment of Radiology, ASST Bergamo Est, 24068 Seriate, Italy.
Vincenza GranataRadiology Division, "Istituto Nazionale Tumori IRCCS Fondazione Pascale-IRCCS di Napoli", 80131 Naples, Italy.
Giuliana GiacobbeDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Gaetano Maria RussoDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Assunta GrilloDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Angela De LisioDiagnostic Imaging Unit, "Azienda Ospedaliera di Rilievo Nazionale Giuseppe Moscati", 83100 Avellino, Italy.
Cesare PauraDiagnostic Imaging Unit, "Azienda Ospedaliera di Rilievo Nazionale Giuseppe Moscati", 83100 Avellino, Italy.
Alfredo ClementeDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Giuliano GagliardiDiagnostic Imaging Unit, "Azienda Ospedaliera di Rilievo Nazionale Giuseppe Moscati", 83100 Avellino, Italy.
Simona MagliocchettiDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Diletta CozziDivision of Radiodiagnostic, Azienda Ospedaliero-Universitaria Careggi, 50139 Firenze, Italy.ORCID 0000-0001-7028-9047
Roberta FuscoRadiology Division, "Istituto Nazionale Tumori IRCCS Fondazione Pascale-IRCCS di Napoli", 80131 Naples, Italy.ORCID 0000-0002-0469-9969
Maria Paola BelfioreDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Roberta GrassiDivision of Radiodiagnostic, "Università degli Studi della Campania Luigi Vanvitelli", 80138 Naples, Italy.
Vittorio MieleDivision of Radiodiagnostic, Azienda Ospedaliero-Universitaria Careggi, 50139 Firenze, Italy.ORCID 0000-0002-7848-1567

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare different commercial software in the quantification of Pneumonia Lesions in COVID-19 infection and to stratify the patients based on the disease severity using on chest computed tomography (CT) images. MATERIALS AND

methodsWe retrospectively examined 162 patients with confirmed COVID-19 infection by reverse transcriptase-polymerase chain reaction (RT-PCR) test. All cases were evaluated separately by radiologists (visually) and by using three computer software programs: (1) Thoracic VCAR software, GE Healthcare, United States; (2) Myrian, Intrasense, France; (3) InferRead, InferVision Europe, Wiesbaden, Germany. The degree of lesions was visually scored by the radiologist using a score on 5 levels (none, mild, moderate, severe, and critic). The parameters obtained using the computer tools included healthy residual lung parenchyma, ground-glass opacity area, and consolidation volume. Intraclass coefficient (ICC), Spearman correlation analysis, and non-parametric tests were performed.

resultsThoracic VCAR software was not able to perform volumes segmentation in 26/162 (16.0%) cases, Myrian software in 12/162 (7.4%) patients while InferRead software in 61/162 (37.7%) patients. A great variability (ICC ranged for 0.17 to 0.51) was detected among the quantitative measurements of the residual healthy lung parenchyma volume, GGO, and consolidations volumes calculated by different computer tools. The overall radiological severity score was moderately correlated with the residual healthy lung parenchyma volume obtained by ThoracicVCAR or Myrian software, with the GGO area obtained by the ThoracicVCAR tool and with consolidation volume obtained by Myrian software. Quantified volumes by InferRead software had a low correlation with the overall radiological severity score.

conclusionsComputer-aided pneumonia quantification could be an easy and feasible way to stratify COVID-19 cases according to severity; however, a great variability among quantitative measurements provided by computer tools should be considered.

Indexed as

Coronavirus InfectionsCOVID-19Diagnosis, Computer-AssistedFeasibility StudiesHumansPandemicsPneumonia, ViralRetrospective StudiesSeverity of Illness IndexSoftwareTomography, X-Ray Computedcomputed tomographycomputer-aided quantificationCOVID-19

Identifiers

PMID32971756
PMCPMC7558768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.