Evidence map›Paper›PMID 32971625›Full record

ReviewIndian journal of ophthalmology2020

Combined retinal vascular occlusion: Demography, clinical features, visual outcome, systemic co-morbidities, and literature review.

Vishal Raval, Sameera Nayak, Merlin Saldanha, Subhadra Jalali, Rajeev Reddy Pappuru, Raja Narayanan, Taraprasad Das

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  4. Review
  5. Sudden Visual Loss After Vitreoretinal Surgery: A Case Report.Case reports in ophthalmological medicine · 2024
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  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vishal RavalLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
Sameera NayakLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
Merlin SaldanhaLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
Subhadra JalaliLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
Rajeev Reddy PappuruLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
Raja NarayananLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
Taraprasad DasLV Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India.
L V Prasad Eye Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo document the clinical features, systemic association, and treatment outcome of patients with a combined retinal vein and artery occlusion (CRVAO) and review of literature.

methodsA retrospective chart review of patients diagnosed with CRVAO at a tertiary eye care center. Patient's demographic details and associated ocular and systemic factors were recorded. Treatment included laser photocoagulation, anti-vascular endothelial growth factor (VEGF) intravitreal injection or transscleral cyclophotocoagulation (TSCPC), alone or in combination. At last, follow- up treatment response was measured in visual acuity status, regression of neovascularization, and control of intraocular pressure (IOP). All cases reported in the current decade were analyzed and compared with this study.

resultsSeventeen eyes with CRVAO accounted for 0.3% of total vascular occlusion (total 5151 patients were seen in this period). The mean age was 48.12 ± 17.5 years (range: 12-87 years) and there were 9 females. Nine eyes had CRVO + CRAO; 6 eyes had BRVO + BRAO, and one patient each had CRVO + BRAO and CRAO + BRVO. Fluorescein angiography (FA) showed delayed 'arm to retina' time (>20 seconds) in all 10 eyes and delayed arteriovenous transit time in 9 out of 10 eyes. Optical coherence tomography (OCT) showed hypereflective inner retinal layers (16 eyes) and neurosensory detachment (7 eyes). The most common systemic associations were hypertension and dyslipidemia (n = 7 people; 41.18%) each. Four patients (23.5%) had a plaque in carotid arteries with normal 2D echocardiography. Ten (59%) eyes were treated with intravitreal bevacizumab + laser; four (23.5%) eyes were treated with laser only, and three (17.6%) eyes were treated with laser + anti-VEGF + TSCPC. At last follow up, vision improved in 9 (52.9%) eyes; stable in 3 (17.7%) eyes, and reduced to perception of light in 5 (29.4%) eyes.

conclusionCombined CRVAO is a rare emergency leading to acute vision loss. Early diagnosis and treatment for ocular complications and systemic evaluation for cardiovascular risk factors are needed.

Indexed as

Retinal Vein OcclusionAdultAgedAngiogenesis InhibitorsBevacizumabDemographyFemaleHumansIntravitreal InjectionsMiddle AgedMorbidityRetrospective StudiesTomography, Optical CoherenceAngiogenesis InhibitorsBevacizumabCardiovascular factorscombined retinal artery and vein occlusionintravitreal bevacizumablaser photocoagulation

Identifiers

PMID32971625
PMCPMC7727993
OpenAlexW3088082778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.