Evidence map›Paper›PMID 32971267›Full record

ArticleNeuroImage2021

Approximating anatomically-guided PET reconstruction in image space using a convolutional neural network.

Georg Schramm, David Rigie, Thomas Vahle, Ahmadreza Rezaei, Koen Van Laere, Timothy Shepherd, Johan Nuyts, Fernando Boada

Abstract read
In one paragraph

Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. PET image denoising based on denoising diffusion probabilistic model.European journal of nuclear medicine and molecular imaging · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Poster Presentations.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Machine Learning Algorithms in Neuroimaging: An Overview.Acta neurochirurgica. Supplement · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Georg SchrammDepartment of Imaging and Pathology, Division of Nuclear Medicine, KU/UZ Leuven, Leuven, Belgium. Electronic address: georg.schramm@kuleuven.be.
David RigieCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, NYC, US.
Thomas VahleSiemens Healthcare GmbH, Erlangen, Germany.
Ahmadreza RezaeiDepartment of Imaging and Pathology, Division of Nuclear Medicine, KU/UZ Leuven, Leuven, Belgium.
Koen Van LaereDepartment of Imaging and Pathology, Division of Nuclear Medicine, KU/UZ Leuven, Leuven, Belgium.
Timothy ShepherdDepartment of Neuroradiology, NYU Langone Health, Department of Radiology, New York University School of Medicine, New York, US.
Johan NuytsDepartment of Imaging and Pathology, Division of Nuclear Medicine, KU/UZ Leuven, Leuven, Belgium.
Fernando BoadaCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, NYC, US.

Funding

Research Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Christopher M Collins · 2014 to 2026
$19.3M
NIA NIH HHS P30 AG066512NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

In the last two decades, it has been shown that anatomically-guided PET reconstruction can lead to improved bias-noise characteristics in brain PET imaging. However, despite promising results in simulations and first studies, anatomically-guided PET reconstructions are not yet available for use in routine clinical because of several reasons. In light of this, we investigate whether the improvements of anatomically-guided PET reconstruction methods can be achieved entirely in the image domain with a convolutional neural network (CNN). An entirely image-based CNN post-reconstruction approach has the advantage that no access to PET raw data is needed and, moreover, that the prediction times of trained CNNs are extremely fast on state of the art GPUs which will substantially facilitate the evaluation, fine-tuning and application of anatomically-guided PET reconstruction in real-world clinical settings. In this work, we demonstrate that anatomically-guided PET reconstruction using the asymmetric Bowsher prior can be well-approximated by a purely shift-invariant convolutional neural network in image space allowing the generation of anatomically-guided PET images in almost real-time. We show that by applying dedicated data augmentation techniques in the training phase, in which 16 [

Indexed as

Neural Networks, ComputerPositron-Emission TomographyBrainFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNortropanesRadiopharmaceuticalsTyrosine(18F)fluoroethyltyrosine(E)-N-(3-iodoprop-2-enyl)-2beta-carbofluoroethoxy-3beta-(4'-methyl-phenyl) nortropaneFluorodeoxyglucose F18NortropanesRadiopharmaceuticalsTyrosineImage reconstructionMachine learningMagnetic resonance imagingMolecular imagingQuantification

Identifiers

PMID32971267
PMCPMC7812485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.