Evidence map›Paper›PMID 32971149›Full record

ReviewImmunology letters2020

Interplays between inflammasomes and viruses, bacteria (pathogenic and probiotic), yeasts and parasites.

Hanna Antushevich

Open access · greenAbstract readReview
In one paragraph

Review in Immunology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Bioactive Polysaccharides fromFoods (Basel, Switzerland) · 2024
    Review
  3. Molecules (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Regulatory Ability ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Molecular biology of autoinflammatory diseases.Inflammation and regeneration · 2021
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Anandamide Influences Interleukin-1β Synthesis andAnimals : an open access journal from MDPI · 2021
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Hanna AntushevichThe Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Department of Genetic Engineering, Instytucka 3, 05-110 Jabłonna, Poland. Electronic address: a.antuszewicz@ifzz.pl.
Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, scientists studying the molecular mechanisms of inflammation have discovered an amazing phenomenon - the inflammasome - a component of the innate immune system that can regulate the functional activity of effector cells during inflammation. At present, it is known that inflammasomes are multimolecular complexes (cytosolic multiprotein oligomers of the innate immune system) that contain many copies of receptors recognizing the molecular structures of cell-damaging factors and pathogenic agents. Inflammasomes are mainly formed in myeloid cells, and their main function is participation in the cleavage of the pro-IL-1β and pro-IL-18 cytokines into their biologically active forms (IL-1β, IL-18). Each type of microorganism influences particular inflammasome activation, and long-term exposure of the organism to viruses, bacteria, yeasts or parasites, among others, can induce uncontrolled inflammation and autoinflammatory diseases. Therefore, this review aims to present the most current scientific data on the molecular interplay between inflammasomes and particular microorganisms. Knowledge about the mechanisms responsible for the interaction between the host and certain types of microorganisms could contribute to the individuation of innovative strategies for the treatment of uncontrolled inflammation targeting a specific type of inflammasome activated by a specific type of pathogen.

Indexed as

Immunity, InnateAnimalsBacteriaCommunicable DiseasesCytokinesHost-Pathogen InteractionsHumansInflammasomesInflammationInflammation MediatorsParasitesSignal TransductionVirusesYeastsCytokinesInflammasomesInflammation MediatorsCoronavirusesInflammasomesParasitesPathogenic and probiotic bacteriaVirusesYeasts

Identifiers

PMID32971149
PMCPMC7505743
OpenAlexW3088134948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.