Evidence map›Paper›PMID 32970979›Full record

ArticleJournal of biomedical nanotechnology2020

Retinoic Acid-Loaded Poly(lactic-

Xianwen Yi, Ying Wang, Zhenquan Jia, Sylvia Hiller, Jun Nakamura, J Christopher Luft, Shaomin Tian, Joseph M DeSimone

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical nanotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Mitigating atherosclerosis: Integrating vaccines with gene targets.American heart journal plus : cardiology research and practice · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xianwen Yi
Ying Wang
Zhenquan Jia
Sylvia Hiller
Jun Nakamura
J Christopher Luft
Shaomin Tian
Joseph M DeSimone

Funding

Delivery of Biological Therapeutics: Using Engineered Particles and Novel DeliverDP1OD006432 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DESIMONE, JOSEPH M. · 2009 to 2011
$2.2M
NIH HHS DP1 OD006432
6 · The paper itself

Abstract

We developed a vaccine formulation containing ApoB derived P210 peptides as autoantigens, retinoic acid (RA) as an immune enhancer, both of which were delivered using PLGA nanoparticles. The formula was used to induce an immune response in 12-week-old male

Indexed as

AtherosclerosisNanoparticlesAnimalsApolipoprotein B-100MaleMicePeptidesPolylactic Acid-Polyglycolic Acid CopolymerTretinoinApolipoprotein B-100PeptidesPolylactic Acid-Polyglycolic Acid CopolymerTretinoin

Identifiers

PMID32970979
PMCPMC8034552
OpenAlexW3088396233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.