Evidence map›Paper›PMID 32970962›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Endotypic Mechanisms of Successful Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea.

Sara Op de Beeck, Andrew Wellman, Marijke Dieltjens, Kingman P Strohl, Marc Willemen, Paul H Van de Heyning, Johan A Verbraecken, Olivier M Vanderveken, Scott A Sands, STAR Trial Investigators

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07337239 (Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy), which is not on this map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07337239 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy

TypeinterventionalSponsorUniversity Hospital, AntwerpRan2026 to 2027Enrolled21ConditionsObstructive Sleep ApneaArmsAdditional measurements during clinical standard follow-up drug-induced sleep endoscopy (DISE)
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2021
    Guideline
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. The importance of classifying central hypopneas: a call to action.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. The upper airway in obstructive sleep apnoea: state of the art.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. [Surgical treatment of adult obstructive sleep apnea].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
  19. Review
  20. Highlights of the Sleep and Breathing Conference 2025.Breathe (Sheffield, England) · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Sara Op de BeeckTranslational Neurosciences, Faculty of Medicine and Health Sciences, and.ORCID 0000-0002-5978-9814
Andrew WellmanDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and.
Marijke DieltjensTranslational Neurosciences, Faculty of Medicine and Health Sciences, and.
Kingman P StrohlDepartment of Medicine, Case Western Reserve University, Cleveland, Ohio.
Marc WillemenMultidisciplinary Sleep Disorders Centre, and.
Paul H Van de HeyningTranslational Neurosciences, Faculty of Medicine and Health Sciences, and.
Johan A VerbraeckenLaboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Olivier M VandervekenTranslational Neurosciences, Faculty of Medicine and Health Sciences, and.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and.
STAR Trial Investigators
University of Antwerp · BEBrigham and Women's Hospital · USRoyal National Throat Nose and Ear Hospital · GBAntwerp University Hospital · BECase Western Reserve University · US

Funding

A Novel Pharmacological Therapy for Obstructive Sleep ApneaR01HL146697 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SANDS, SCOTT A · 2019 to 2023
$3.4M
NHLBI NIH HHS R01 HL146697
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overFemaleHumansHypoglossal NerveMaleMiddle AgedSleep Apnea, ObstructiveTranscutaneous Electric Nerve StimulationTreatment Outcomearousal thresholdpathophysiologyprecision medicinesleep-disordered breathingupper airway stimulation

Identifiers

PMID32970962
PMCPMC7958511
OpenAlexW3089077069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.