Evidence map›Paper›PMID 32970861›Full record

ReviewJournal of neurochemistry2021

Viral infection and smell loss: The case of COVID-19.

Isaias Glezer, Alexandre Bruni-Cardoso, Deborah Schechtman, Bettina Malnic

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of neurochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Isaias GlezerDepartment of Biochemistry, UNIFESP, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Tres de Maio, São Paulo, Brazil.ORCID 0000-0002-9799-1933
Alexandre Bruni-CardosoDepartment of Biochemistry, University of São Paulo, São Paulo, Brazil.ORCID 0000-0003-3475-2190
Deborah SchechtmanDepartment of Biochemistry, University of São Paulo, São Paulo, Brazil.ORCID 0000-0002-8874-7023
Bettina MalnicDepartment of Biochemistry, University of São Paulo, São Paulo, Brazil.ORCID 0000-0002-5877-4784
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São PauloFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2013/07937-8Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2016/24471-0Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2018/18633-3Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2019/06982-6Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2019/26767-2
6 · The paper itself

Abstract

Olfactory disorders have been increasingly reported in individuals infected with SARS-CoV-2, the virus causing the coronavirus disease 2019 (COVID-19). Losing the sense of smell has a strong impact on the quality of life, since it may lead to malnutrition, weight loss, food poisoning, depression, and exposure to dangerous chemicals. Individuals who suffer from anosmia (inability to smell) also cannot sense the flavor of food, which is a combination of taste and smell. Interestingly, infected individuals have reported sudden loss of smell with no congested nose, as is frequently observed in common colds or other upper respiratory tract infections. These observations suggest that SARS-CoV-2 infection leads to olfactory loss through a distinct mechanism, which is still unclear. This article provides an overview of olfactory loss and the recent findings relating to COVID-19. Possible mechanisms of SARS-CoV-2-induced olfactory loss are also discussed.

Indexed as

COVID-19HumansOlfaction DisordersOlfactory Receptor NeuronsVirus Diseasesanosmiacoronavirusolfactionolfactory sensory neuronSARS-CoV-2smell loss

Identifiers

PMID32970861
PMCPMC7537178
OpenAlexW3088918526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.