Evidence map›Paper›PMID 32970793›Full record

ArticleThe Journal of cell biology2020

Inflammasomes: Exosomal miRNAs loaded for action.

Sampsa Matikainen, Tuula A Nyman, Wojciech Cypryk

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Sampsa MatikainenHelsinki Rheumatic Disease and Inflammation Research Group, Translational Immunology Research Program, University of Helsinki, Helsinki University Clinicum, Helsinki, Finland.
Tuula A NymanDepartment of Immunology, Institute of Clinical Medicine, University of Oslo and Rikshospitalet, Oslo, Norway.
Wojciech CyprykCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Lodz, Poland.
Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk · PLUniversity of Helsinki · FIUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammasomes are multiprotein complexes of the innate immune system. Their activation leads to robust secretion of exosomes. In this issue, Wozniak et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201912074) reveal a connection between inflammasome-mediated cleavage of Rab-interacting lysosomal protein (RILP) and sequence-specific loading of miRNAs into exosomes.

Indexed as

ExosomesMicroRNAsAdaptor Proteins, Signal TransducingFragile X Messenger Ribonucleoprotein 1HumansInflammasomesInflammationRNA-Binding ProteinsAdaptor Proteins, Signal TransducingFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1InflammasomesMicroRNAsRILP protein, humanRNA-Binding Proteins

Identifiers

PMID32970793
PMCPMC7659727
OpenAlexW3089104647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.