Evidence map›Paper›PMID 32970774›Full record

ArticlePloS one2020

Complications and mortality of cardiovascular emergency admissions during COVID-19 associated restrictive measures.

Heiko Bugger, Johannes Gollmer, Gudrun Pregartner, Gerit Wünsch, Andrea Berghold, Andreas Zirlik, Dirk von Lewinski

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Ethical Lessons from an Intensivist's Perspective.Journal of clinical medicine · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Management of cardiogenic shock.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021
    Review
  19. Article
  20. Impact of COVID-19 on aortic operations.Seminars in vascular surgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Heiko BuggerDivision of Cardiology, Medical University of Graz, Graz, Austria.
Johannes GollmerDivision of Cardiology, Medical University of Graz, Graz, Austria.ORCID 0000-0002-8734-6359
Gudrun PregartnerInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Gerit WünschInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Andrea BergholdInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Andreas ZirlikDivision of Cardiology, Medical University of Graz, Graz, Austria.
Dirk von LewinskiDivision of Cardiology, Medical University of Graz, Graz, Austria.ORCID 0000-0001-9996-6128
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While hospital admissions for myocardial infarction (MI) and pulmonary embolism (PE) are decreased during the COVID-19 pandemic, controversy remains about respective complication and mortality rates. This study evaluated admission rates, complications, and intrahospital mortality for selected life-threatening cardiovascular emergencies (MI, PE, and acute aortic dissection (AAD)) during COVID-19-associated restrictive social measures (RM) in Styria, Austria. By screening a patient information system for International Statistical Classification of Diseases and Related Health Problems (ICD) diagnosis codes covering more than 85% of acute hospital admissions in the state of Styria (~1.24 million inhabitants), we retrospectively identified patients with admission diagnoses for MI (I21, I22), PE (I26), and AAD (I71). Rates of complications such as cardiogenic shock and cardiopulmonary resuscitation, treatment escalations (thrombolysis for PE), and mortality were analyzed by patient chart review during 6 weeks following onset of COVID-19 associated RM, and during respective time frames in the years 2016 to 2019. 1,668 patients were included. Cumulative admissions for MI, PE and AAD decreased (RR 0.77; p<0.001) during RM compared to previous years. In contrast, intrahospital mortality increased by 65% (RR 1.65; p = 0.041), mainly driven by mortality following MI (RR 1.80; p = 0.042). PE patients received more frequently thrombolysis treatment (RR 3.63; p = 0.006), while rates of cardiogenic shock and cardiopulmonary resuscitation remained unchanged. Of 226 patients hospitalized during RM, 81 patients with suspected COVID-19 disease were screened for SARS-CoV-2 infection with only 5 testing positive. Thus, cumulative hospital admissions for cardiovascular emergencies decreased during COVID-19 associated RM while intrahospital mortality increased.

Indexed as

AgedAged, 80 and overAortic DissectionAustriaBetacoronavirusCoronavirus InfectionsCOVID-19Emergency Service, HospitalFemaleHospitalizationHospital MortalityHumansMaleMiddle AgedMyocardial InfarctionPandemics

Identifiers

PMID32970774
PMCPMC7514100
OpenAlexW3088858888

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.