Evidence map›Paper›PMID 32969790›Full record

ArticleeLife2020

Hedgehog signaling is required for endomesodermal patterning and germ cell development in the sea anemone

Cheng-Yi Chen, Sean A McKinney, Lacey R Ellington, Matthew C Gibson

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cheng-Yi ChenStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0002-0520-346X
Sean A McKinneyStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0002-9740-6247
Lacey R EllingtonStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0003-0872-5455
Matthew C GibsonStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0001-5588-8842
Stowers Institute for Medical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two distinct mechanisms for primordial germ cell (PGC) specification are observed within Bilatera: early determination by maternal factors or late induction by zygotic cues. Here we investigate the molecular basis for PGC specification in

Indexed as

Germ LayersHedgehog ProteinsSea AnemonesAnimalsBody PatterningFemaleGene Knockdown TechniquesGerm CellsLife Cycle StagesMaleSignal TransductionHedgehog Proteinsdevelopmental biologyendomesodermal patterningevolutionary biologygerm cell developmentNematostella vectensiszygotic hedgehog signaling

Identifiers

PMID32969790
PMCPMC7515634
OpenAlexW3088839321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.