Evidence map›Paper›PMID 32969788›Full record

ArticleEmerging infectious diseases2020

Sensitive Detection of SARS-CoV-2-Specific Antibodies in Dried Blood Spot Samples.

Gabriella L Morley, Stephen Taylor, Sian Jossi, Marisol Perez-Toledo, Sian E Faustini, Edith Marcial-Juarez, Adrian M Shields, Margaret Goodall, Joel D Allen, Yasunori Watanabe and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Gabriella L Morley
Stephen Taylor
Sian Jossi
Marisol Perez-Toledo
Sian E Faustini
Edith Marcial-Juarez
Adrian M Shields
Margaret Goodall
Joel D Allen
Yasunori Watanabe
Maddy L Newby
Max Crispin
Mark T Drayson
Adam F Cunningham
Alex G Richter
Matthew K O'Shea
University of Oxford · GBSave the Children · BDUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity of Birmingham · GBUniversity of Southampton · GB

Funding

Identification of neutralizing epitopes on SARS-CoV-2 spike for design of vaccines and small-molecule antiviralsUM1AI144462 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BURTON, DENNIS R. · 2019 to 2025
$201.6M
Gates Foundation INV-008813Medical Research Council MC_PC_17183NIAID NIH HHS UM1 AI144462Wellcome Trust
6 · The paper itself

Abstract

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.

Indexed as

Antibodies, ViralCase-Control StudiesCOVID-19COVID-19 Serological TestingDried Blood Spot TestingHumansPredictive Value of TestsSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibodycoronavirus diseaseCOVID-19DBSdried blood spotrespiratory infectionsSARS-CoV-2severe acute respiratory syndrome coronavirus 2viruseszoonoses

Identifiers

PMID32969788
PMCPMC7706975
OpenAlexW3088125306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.