Evidence map›Paper›PMID 32969562›Full record

Trial reportHuman brain mapping2020

Mindfulness training preserves sustained attention and resting state anticorrelation between default-mode network and dorsolateral prefrontal cortex: A randomized controlled trial.

Clemens C C Bauer, Liron Rozenkrantz, Camila Caballero, Alfonso Nieto-Castanon, Ethan Scherer, Martin R West, Michael Mrazek, Dawa T Phillips, John D E Gabrieli, Susan Whitfield-Gabrieli

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Default Mode Network Functional Connectivity As a Transdiagnostic Biomarker of Cognitive Function.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Clemens C C BauerDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0002-3481-4438
Liron RozenkrantzDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Camila CaballeroDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Alfonso Nieto-CastanonDepartment of Psychology, Northeastern University, Boston, Massachusetts, USA.
Ethan SchererHarvard Graduate School of Education, Cambridge, Massachusetts, USA.
Martin R WestHarvard Graduate School of Education, Cambridge, Massachusetts, USA.
Michael MrazekDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, California, USA.
Dawa T PhillipsEmpowerment Holdings, Santa Barbara, California, USA.
John D E GabrieliDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Susan Whitfield-GabrieliDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

Funding

Consejo Nacional de Ciencia y Tecnología 250718Poitras Center for Psychiatric Disorders Research at the McGovern Institute for Brain ResearchWalton Family Foundation
6 · The paper itself

Abstract

Mindfulness training can enhance cognitive control, but the neural mechanisms underlying such enhancement in children are unknown. Here, we conducted a randomized controlled trial (RCT) with sixth graders (mean age 11.76 years) to examine the impact of 8 weeks of school-based mindfulness training, relative to coding training as an active control, on sustained attention and associated resting-state functional brain connectivity. At baseline, better performance on a sustained-attention task correlated with greater anticorrelation between the default mode network (DMN) and right dorsolateral prefrontal cortex (DLPFC), a key node of the central executive network. Following the interventions, children in the mindfulness group preserved their sustained-attention performance (i.e., fewer lapses of attention) and preserved DMN-DLPFC anticorrelation compared to children in the active control group, who exhibited declines in both sustained attention and DMN-DLPFC anticorrelation. Further, change in sustained-attention performance correlated with change in DMN-DLPFC anticorrelation only within the mindfulness group. These findings provide the first causal link between mindfulness training and both sustained attention and associated neural plasticity. Administered as a part of sixth graders' school schedule, this RCT supports the beneficial effects of school-based mindfulness training on cognitive control.

Indexed as

ConnectomeMindfulnessAttentionChildDefault Mode NetworkDorsolateral Prefrontal CortexExecutive FunctionFemaleHumansMaleNerve NetNeuronal PlasticityPsychomotor Performancechildrendefault mode networkfunctional connectivitymindfulness trainingresting statesustained attention

Identifiers

PMID32969562
PMCPMC7670646

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.