Evidence map›Paper›PMID 32968719›Full record

ArticleMaterialia2020

Calcium phosphate enriched synthetic tyrosine-derived polycarbonate - dicalcium phosphate dihydrate polymer scaffolds for enhanced bone regeneration.

Shruti Saxena, Wei Chang, Amir Fakhrzadeh, N Sanjeeva Murthy, Weibo Zhang, Joachim Kohn, Pamela C Yelick

Open access · greenAbstract read
In one paragraph

Article in Materialia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shruti SaxenaNew Jersey Center for Biomaterials, Rutgers University, Piscataway, New Jersey.
Wei ChangNew Jersey Center for Biomaterials, Rutgers University, Piscataway, New Jersey.
Amir FakhrzadehNew Jersey Center for Biomaterials, Rutgers University, Piscataway, New Jersey.
N Sanjeeva MurthyNew Jersey Center for Biomaterials, Rutgers University, Piscataway, New Jersey.
Weibo ZhangDepartment of Orthodontics, Division of Craniofacial and Molecular Genetics, Tufts University School of Dental Medicine, Boston, Massachusetts 02111.
Joachim KohnNew Jersey Center for Biomaterials, Rutgers University, Piscataway, New Jersey.
Pamela C YelickDepartment of Orthodontics, Division of Craniofacial and Molecular Genetics, Tufts University School of Dental Medicine, Boston, Massachusetts 02111.
Rutgers, The State University of New Jersey · USTufts University · US

Funding

Translational Research in Regenerative MedicineT32EB005583 · NIBIB · RUTGERS, THE STATE UNIV OF N.J. · PI LEE, KIBUM, PAREKKADAN, BIJU · 2006 to 2022
$4.7M
Bioengineered Composite Alveolar Bone-Tooth Constructs for Tooth RegenerationR01DE026731 · NIDCR · TUFTS UNIVERSITY BOSTON · PI YELICK, PAMELA C · 2017 to 2021
$3.6M
NIBIB NIH HHS T32 EB005583NIDCR NIH HHS R01 DE026731
6 · The paper itself

Abstract

Optimal repair of large craniomaxillofacial (CMF) defects caused by trauma or disease requires the development of new, synthetic osteoconductive materials in combination with cell-based therapies, to overcome the limitations of traditionally used bone graft substitutes. In this study, tyrosine-derived polycarbonate, E1001(1k) scaffolds were fabricated to incorporate the osteoinductive coating, Dicalcium phosphate dihydrate (DCPD). The biocompatibility of E1001(1k)-DCPD, E1001(1k)-βTCP and E1001(1k) scaffolds was compared using

Indexed as

dental pulp stem cellsDPCDosteogenic differentiationtyrosine derived scaffolds

Identifiers

PMID32968719
PMCPMC7505226
OpenAlexW3004505285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.