Evidence map›Paper›PMID 32968699›Full record

ArticleNanoImpact2020

Acute

Nathanial J Parizek, Benjamin R Steines, Ezazul Haque, Ralph Altmaier, Andrea Adamcakova-Dodd, Patrick T O'Shaughnessy, Peter S Thorne

Open access · greenAbstract read
In one paragraph

Article in NanoImpact, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nathanial J ParizekInterdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, IA 52246.
Benjamin R SteinesDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, IA 52246.
Ezazul HaqueInterdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, IA 52246.
Ralph AltmaierDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, IA 52246.
Andrea Adamcakova-DoddDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, IA 52246.
Patrick T O'ShaughnessyDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, IA 52246.
Peter S ThorneInterdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, IA 52246.ORCID 0000-0002-5045-0929
University of Iowa · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Engineered Nanomaterial Synthesis, Characterization and Method Development Center for Nano-safety ResearchU24ES026946 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI DEMOKRITOU, PHILIP · 2016 to 2020
$3.8M
Immunomodulation Potential of Inhaled Engineered Nanomaterials as an Adverse Outcome PathwayU01ES027252 · NIEHS · UNIVERSITY OF IOWA · PI THORNE, PETER S · 2016 to 2020
$2.1M
NIEHS NIH HHS P30 ES005605NIEHS NIH HHS U01 ES027252NIEHS NIH HHS U24 ES026946
6 · The paper itself

Abstract

Cellulose nanofibers (CNFs) are an emerging engineered nanomaterial that are utilized in a variety of applications, including as a replacement for urea-formaldehyde, and other adhesives, as the binding agent in manufactured fiber and particle boards. To ensure the health and well-being of those producing, installing, or otherwise using cellulose nanofiber boards (CNFBs) it is imperative that the particulate matter (PM) produced during CNFB manipulation be evaluated for toxicity. We developed and internally verified a generation system to examine the PM produced by sanding CNFB using aluminum oxide sandpaper. With 80-grit sandpaper our system produced a low dispersity aerosol, as determined by a scanning mobility particle sizer and an optical particle counter, with a geometric mean of 28 nm (GSD = 1.60). ICP-MS evaluation showed little difference in metal concentrations between CNFB PM and nonsanded CNFB stock. We then used the system to simultaneously generate and expose both male and female C57BL/6J mice acutely for 4 hours at a concentration of 7.9 mg/m

Identifiers

PMID32968699
PMCPMC7504912
OpenAlexW3005197768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.