Evidence map›Paper›PMID 32968635›Full record

ArticleCardiovascular diagnosis and therapy2020

Study on the mechanism of anti-MIRI action of total flavones of Fructus Chorspondiatis by PET/CT imaging.

Guo-Jian Zhang, Li-Hong Wei, Hai-Wen Lu, Yun-Feng Xiao, Wen-Rui Wang, Yu-Lin He, Xue-Mei Wang, Jia-He Tian

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Guo-Jian ZhangMedical School of Chinese PLA, Beijing, China.
Li-Hong WeiDepartment of Pharmacy, Inner Mongolia International Mongolian Hospital, Hohhot, China.
Hai-Wen LuDepartment of Imaging, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Yun-Feng XiaoCenter for New Drug Safety Evaluation and Research, Inner Mongolia Medical University, Hohhot, China.
Wen-Rui WangDepartment of Nuclear Medicine, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Yu-Lin HeDepartment of Nuclear Medicine, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Xue-Mei WangDepartment of Nuclear Medicine, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Jia-He TianMedical School of Chinese PLA, Beijing, China.
Inner Mongolia Medical University · CNPLA Academy of Military Science · CNInner Mongolia International Mongolian Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate anti myocardial ischemia/reperfusion injury (MIRI) action of total flavones of Fructus Chorspondiatis (TFFC) in rats by

methodsMale Sprague-Dawley rats were randomly divided into 6 groups. Micro PET/CT imaging was performed before and after modeling to calculate the volume (VOI) and SUV

resultsThe imaging viscosities of the imaging agents were observed at 24 and 48 h in each group. The VOI of 24 h imaging was (6.33±2.02), (6.01±1.56) and (3.32±0.86) mm

conclusionsThe PET/CT imaging method can detect non-invasive, in vivo and dynamic MIRI, and can accurately evaluate the protective effect of traditional Mongolian medicine TFFC on MIRI. The Anti-MIRI of TFFC can scavenge free radicals, reduce oxidative stress damage, inhibit apoptosis, affect the activity of related enzymes.

Indexed as

myocardial ischemia/reperfusion injury (MIRI)position emission tomography/computed tomography (PET/CT)Total flavones of Fructus Chorspondiatis (TFFC)

Identifiers

PMID32968635
PMCPMC7487392
OpenAlexW3042391365

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.