Evidence map›Paper›PMID 32968615›Full record

ArticleIn silico pharmacology2020

Insight into glycogen synthase kinase-3β inhibitory activity of phyto-constituents from

Opeyemi Iwaloye, Olusola Olalekan Elekofehinti, Emmanuel Ayo Oluwarotimi, Babatom Iwa Kikiowo, Toyin Mary Fadipe

Abstract read
In one paragraph

Article in In silico pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Computational identification ofBioinformatics advances · 2026
    Article
  2. Article
  3. Article
  4. Role of Saponins fromMolecules (Basel, Switzerland) · 2025
    Article
  5. Identification of phyto-compounds fromIn silico pharmacology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Journal of diabetes and metabolic disorders · 2021
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Opeyemi IwaloyeBioinformatics and Molecular Biology Unit, Department of Biochemistry, Federal University of Technology, Akure, Ondo State Nigeria.ORCID 0000-0001-6128-2900
Olusola Olalekan ElekofehintiBioinformatics and Molecular Biology Unit, Department of Biochemistry, Federal University of Technology, Akure, Ondo State Nigeria.
Emmanuel Ayo OluwarotimiBioinformatics and Molecular Biology Unit, Department of Biochemistry, Federal University of Technology, Akure, Ondo State Nigeria.
Babatom Iwa KikiowoBioinformatics and Molecular Biology Unit, Department of Biochemistry, Federal University of Technology, Akure, Ondo State Nigeria.
Toyin Mary FadipeBioinformatics and Molecular Biology Unit, Department of Biochemistry, Federal University of Technology, Akure, Ondo State Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over activity of Glycogen synthase kinase-3β (GSK-3β), a serine/threonine-protein kinase has been implicated in a number of diseases including stroke, type II diabetes and Alzheimer disease (AD). This study aimed to find novel inhibitors of GSK-3β from phyto-constituents of

Indexed as

AutoQSARGlycogen synthase kinase-3βInduced-fit docking (IFD)Melissa officinalisMM-GBSA

Identifiers

PMID32968615
PMCPMC7487069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.