Evidence map›Paper›PMID 32968590›Full record

ArticleCureus2020

Oxaliplatin-Induced Thrombocytopenia: A Case Report and Review of Pathophysiology of Various Speculative Mechanisms.

Haider Ghazanfar, Iqra Nawaz, Nisha Ali

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Haider GhazanfarInternal Medicine, BronxCare Health System, Bronx, USA.
Iqra NawazInternal Medicine, BronxCare Health System, Bronx, USA.
Nisha AliInternal Medicine, BronxCare Health System, Bronx, USA.
MemorialCare Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxaliplatin is one of the most common anti-neoplastic agents used in the treatment of small bowel adenocarcinoma. Peripheral neuropathy is one of the most common side effects of oxaliplatin. Oxaliplatin-induced thrombocytopenia is an extremely rare side effect and can result from various mechanisms. We present a case of a 66-year-old female who presented to the hospital for the ninth cycle of FOLFOX chemotherapy for her small bowel adenocarcinoma. The patient developed severe thrombocytopenia within 24 hours of administration of oxaliplatin. Physicians need to be aware of the sudden onset of severe thrombocytopenia associated with oxaliplatin use as early diagnosis and prompt treatment can prove lifesaving for these patients.

Indexed as

adenocarcinomachemotherapymorbiditymortalityoxaliplatinthrombocytopenia

Identifiers

PMID32968590
PMCPMC7505612
OpenAlexW3081197967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.