ArticleAlgorithms for molecular biology : AMB2020
A linear-time algorithm that avoids inverses and computes Jackknife (leave-one-out) products like convolutions or other operators in commutative semigroups.
Article in Algorithms for molecular biology : AMB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundData about herpesvirus microRNA motifs on human circular RNAs suggested the following statistical question. Consider independent random counts, not necessarily identically distributed. Conditioned on the sum, decide whether one of the counts is unusually large. Exact computation of the p
resultsThis article gives a linear-time Jackknife Product algorithm. Its upward phase constructs a standard segment tree for computing segment products like
conclusionsIn the herpesvirus application, the Jackknife Product algorithm required 15 min; standard segment tree algorithms would have taken an estimated 3 h; and the quadratic algorithm, an estimated 1 month. The Jackknife Product algorithm has many possible uses in bioinformatics and statistics.
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