Evidence map›Paper›PMID 32968402›Full record

ArticlePakistan journal of medical sciences

Association of serum osteoprotegerin with severity of chronic liver disease in female patients: A potential biomarker.

Saba Tariq, Sundus Tariq, Shaista Hussain, Mukhtiar Baig

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Saba TariqSaba Tariq, MBBS, M.Phil. Associate Professor of Pharmacology, University Medical & Dental College, University of Faisalabad, Pakistan, Research Scholar, Pharmacology, University of Health Sciences, Lahore, Pakistan.
Sundus TariqSundus Tariq, MBBS, M.Phil. Associate Professor of Physiology, University Medical & Dental College, Faisalabad, Pakistan. Research Scholar, Physiology, University of Health Sciences, Lahore, Pakistan.
Shaista HussainShaista Hussain, MBBS. House Officer, Allied Hospital Faisalabad, Faisalabad, Pakistan.
Mukhtiar BaigProf. Mukhtiar Baig, MBBS, M.Phil., PhD. Department of Clinical Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah- 21589, KSA.
University of Health Sciences Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the association of serum osteoprotegerin (OPG) with the severity of chronic liver disease in female patients.

methodsThis case-control study was conducted in Madina Teaching Hospital from 2019-2020.An institutional review board of University Medical and Dental College, The University of Faisalabad gave the approval to conduct the study. Only female patients of age group 40 to 60 years having CLD were included in this study. Total 80 participants were enrolled after fulfilling the inclusion and exclusion criteria. Serum OPG levels were measured by enzyme linked immunosorbant assay (ELISA) supplied by ELAB Sciences, USA. The severity of disease was assessed by Child-Pugh classification.

resultsOPG levels were significantly different between the three Child-Pugh classes. OPG levels were significantly high in class C indicating increased level of this cytokine in CLD as compared to class A (

conclusionThe levels of serum Osteoprotegerin is increased in severe form of chronic liver disease (Class C) of Child-Pughs classification as compared to mild (Class A) and moderate (Class B) forms of Child-Pughs classification.

Indexed as

Chronic liver diseaseHepatomegalyliver cirrhosisOsteoprotegerin

Identifiers

PMID32968402
PMCPMC7501019
OpenAlexW3049112956

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.