ArticlePakistan journal of medical sciences
Primary Hyperparathyroidism: Experience from a Tertiary Care Centre in Pakistan.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 3 citations in OpenAlex.
- Spectrum of parathyroid disorders in Pakistan: a review article.Annals of medicine and surgery (2012) · 2025Review
- Efficacy of Vitamin-D supplementation in improving the prognosis of H-type hypertension in elderly patients.Pakistan journal of medical sciences · 2024Article
- Malignant and Non-Malignant Causes of Hypercalcemia: A Retrospective Study at a Tertiary Care Hospital in Pakistan.Cureus · 2021Article
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Authors and funding
4 authors at 2 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the clinical, biochemical and radiological features and management outcomes of patients with primary hyperparathyroidism.
methodsThis retrospective study was conducted at the Aga Khan University Hospital, Karachi, Pakistan and comprised data of patients with primary hyperparathyroidism from 2008 to 2017.
resultsOut of 103 patients, 83(80.6%) were female. Overall mean age was 59.3±16.2 years. Musculoskeletal manifestations were seen in 60(58.3%) patients and renal manifestations in 28(27.2%). Ostieits fibrosa cystica was found in 04(3.88%) patients. Overall, Ultrasound neck and sestamibi scan localized the lesion in 66 (64.1%) and 77 (76.2%) patients respectively. Among 79 patients who underwent surgery, 67 (84.8%) patients had an adenoma, 05 (6.3%) had hyperplasia and 02(2.53%) patients had parathyroid carcinoma whereas histopathology was inconclusive in 5 (6.32%) out of the 79 surgically treated patients. Disease recurrence was seen in 13 out of 79(16.45%) patients who underwent surgery.
conclusionPrimary hyperparathyroidism is associated with significant morbidity in our population. Targeted measures like improving patient awareness, routine calcium screening, vitamin D supplementation and a high index of suspicion by the clinician may help in early diagnosis of the condition and thus reduce morbidity.
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