Evidence map›Paper›PMID 32968287›Full record

ArticleJNMA; journal of the Nepal Medical Association2020

Prevalence of Acute Kidney Injury in Patients with Liver Cirrhosis.

Pukar Thapa, Sudhamshu Kc, Achyut Bikram Hamal, Dilip Sharma, Sandip Khadka, Niyanta Karki, Bikash Jaishi, Pratap Sagar Tiwari, Anshu Vaidya, Anshu Karki

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JNMA; journal of the Nepal Medical Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Review
  6. Review
  7. The Role of UrinaryJournal of clinical medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pukar ThapaLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Sudhamshu KcLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Achyut Bikram HamalLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Dilip SharmaLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Sandip KhadkaLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Niyanta KarkiLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Bikash JaishiLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Pratap Sagar TiwariLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Anshu VaidyaLiver unit, Department of Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Anshu KarkiDepartment of Medicine, Nepal Army Institute of Health Sciences, Kathmandu, Nepal.
Bir Hospital · NPNepalese Army Institute of Health Services · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute kidney injury is a common and life-threatening event in patients with liver cirrhosis occurring in approximately 20-50% of hospitalized patients of liver cirrhosis. Pre-renal acute kidney injury, the hepatorenal syndrome type of acute kidney injury and acute tubular necrosis represent the common causes. The aim of this study was to study the profile of acute kidney injury in patients with liver cirrhosis.

methodsConsecutive patients of liver cirrhosis admitted in Liver unit of Bir Hospital were studied to see the presence of acute kidney injury in this hospital based descriptive cross-sectional study. Clinical and laboratory parameters along with various clinical outcome were compared between different groups categorized by the severity of liver disease and renal dysfunction.

resultsOut of 302 liver cirrhosis patients, 56 (18.5%) had acute kidney injury among which 23 (46%) were found to have pre-renal acute kidney injury, 15 (30%) with hepatorenal syndrome- acute kidney injury and 12 (24%) with intrinsic renal disease. Patients with higher stages of acute kidney injury had longer duration of hospital stay and hepatorenal syndrome-acute kidney injury was seen in patients with higher grade of ascites and with hyponatremia.

conclusionsAcute kidney injury is a common occurrence in patients with advanced liver cirrhosis with pre-renal acute kidney injury being the commonest cause. Median hospital stay is directly affected by the severity of acute kidney injury and hepatorenal syndrome-acute kidney injury was seen in patients with higher grade of ascites and hyponatremia. Early identification of patients at high risk for acute kidney injury may help to reduce mortality and contain costs.

Indexed as

Acute Kidney InjuryHepatorenal SyndromeCross-Sectional StudiesHumansLiver CirrhosisPrevalenceAcute kidney injury; Hepatorenal syndrome; Liver cirrhosis.

Identifiers

PMID32968287
PMCPMC7580368
OpenAlexW3087797408

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.