Evidence map›Paper›PMID 32968280›Full record

ArticleNature2020

Conformation of sister chromatids in the replicated human genome.

Michael Mitter, Catherina Gasser, Zsuzsanna Takacs, Christoph C H Langer, Wen Tang, Gregor Jessberger, Charlie T Beales, Eva Neuner, Stefan L Ameres, Jan-Michael Peters and 3 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 114 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  8. Article
  9. Article
  10. Cohesin activity accelerates the homology search.bioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Review
  13. Cohesin acetylation and ATPase activity control cohesion and loop architecture through distinct mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  14. Exploring the energy landscape of bacterial chromosome segregation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. An electrostatic repulsion model of centromere organisation.bioRxiv : the preprint server for biology · 2025
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Michael MitterInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria. michael.mitter@imba.oeaw.ac.at.
Catherina GasserInstitute of Organic Chemistry and Center for Molecular Biosciences (CMBI), Leopold-Franzens University, Innsbruck, Austria.
Zsuzsanna TakacsInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.ORCID http://orcid.org/0000-0003-4741-6487
Christoph C H LangerInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Wen TangResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.
Gregor JessbergerResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.
Charlie T BealesInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Eva NeunerInstitute of Organic Chemistry and Center for Molecular Biosciences (CMBI), Leopold-Franzens University, Innsbruck, Austria.
Stefan L AmeresInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Jan-Michael PetersResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.
Anton GoloborodkoInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Ronald MicuraInstitute of Organic Chemistry and Center for Molecular Biosciences (CMBI), Leopold-Franzens University, Innsbruck, Austria.
Daniel W GerlichInstitute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria. daniel.gerlich@imba.oeaw.ac.at.ORCID http://orcid.org/0000-0003-1637-3365
Institute of Molecular Biotechnology · ATResearch Institute of Molecular Pathology · AT

Funding

Austrian Science Fund FWF F 8002Austrian Science Fund FWF F 8011Austrian Science Fund FWF P 27947Austrian Science Fund FWF P 31691European Research Council 281198European Research Council 693949
6 · The paper itself

Abstract

The three-dimensional organization of the genome supports regulated gene expression, recombination, DNA repair, and chromosome segregation during mitosis. Chromosome conformation capture (Hi-C)

Indexed as

Chromosome PairingDNA ReplicationNucleic Acid ConformationCell Cycle ProteinsChromatidsChromosomal Proteins, Non-HistoneCohesinsDNAGenome, HumanHeterochromatinHumansCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsDNAHeterochromatin

Identifiers

PMID32968280
PMCPMC7116725
OpenAlexW3088572354

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.