ArticleNature2020
The maternal microbiome modulates fetal neurodevelopment in mice.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 305 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
305citing papers in PubMed, 2 pooled it
23.4field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
305 citing papers in PubMed, 2 syntheses or guidelines pooled it, 527 citations in OpenAlex.
- Prebiotics, probiotics, and synbiotics and maternal mental health during pregnancy and postpartum period: a systematic review.Frontiers in nutrition · 2026Pooled it
- Dietary Patterns and Diet Quality before and/or during Pregnancy and How These Affect Birth Outcomes: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Antenatal depressive symptoms impair offspring neurodevelopment by inducing maternal gut microbiota dysbiosis during pregnancy.Gut microbes · 2026Article
- Gut microbiome and pregnancy complications: emerging evidence and mechanistic insights.Gut microbes · 2026Review
- Parental microbiome programming of early-life neurodevelopment: multi-niche contributions through the microbiome-gut-brain axis.Gut microbes · 2026Review
- Early antibiotic exposure and vaccine immune responses in preterm infants: potential sex-specific differences.Gut microbes · 2026Observational
- Obstetric Pharmacomicrobiomics.Clinical pharmacology and therapeutics · 2026Review
- Prenatal THC Exposure Differentially Alters Gut Physiology and Microbiota in Stress-Resilient and Vulnerable Mice.Pharmaceuticals (Basel, Switzerland) · 2026Article
- A geroprotective probiotic and its functional metabolite counteract inflammaging to extend healthspan.Nature aging · 2026Article
- Article
- Dietary supplementation with selenium yeast during early pregnancy enhances litter size in association with antioxidant capacity, progesterone synthesis, and gut microbiota in sows.Microbiology spectrum · 2026Article
- Maternal and infant gut microbiome.iMeta · 2026Review
- The maternal gut microbiota influences myocardial maturation and diastolic function of offspring in mice.Science China. Life sciences · 2026Article
- Maternal serum from 'high-stress' pregnancies demonstrates bioactivity capable of attenuating neurite growth through a TNFα-dependent pathway in SH-SY5Y cells.Bioscience reports · 2026Article
- Fermented Foods, Functional Nutrition, and Maternal Gut Microbiota During Pregnancy: Molecular Mechanisms and the Maternal-Infant Microbiome Axis.International journal of molecular sciences · 2026Review
- Chemicals in cow milk and soy beverages: Neurotoxicity and neuroprotection.Advances in neurotoxicology · 2026Article
- Intergenerational effects of the microbiota on neurodevelopment: mechanisms and therapeutic perspectives.Acta pharmacologica Sinica · 2026Review
- The Maternal Microbiome in Pregnancy: From Physiological Changes to Dysbiosis and Obstetrical Complications-Therapeutic Perspectives.Life (Basel, Switzerland) · 2026Review
- Gestational dysbiosis is associated with altered early-life microbial seeding and favors pathobiont expansion in offspring.iScience · 2026Article
- Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development.Comprehensive Physiology · 2026Review
245 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Helen E VuongDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA. hvuong2323@gmail.com.ORCID http://orcid.org/0000-0001-7837-8239
Geoffrey N PronovostDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.
Drake W WilliamsOral Immunity and Inflammation Section, NIDCR, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-7718-2098
Elena J L ColeyDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.
Emily L SieglerDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-9007-1934
Austin QiuDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.
Maria KazantsevDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.
Chantel J WilsonDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-0813-8699
Tomiko RendonDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.
Elaine Y HsiaoDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1633-588X
University of California, Los Angeles · USNational Institute of Dental and Craniofacial Research · US
Funding
UPLIFT: UCLA Postdocs' Longitudinal Investment in Faculty TrainingK12GM106996 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CAREY, MICHAEL F, VILLANUEVA, CLAUDIO J · 2016 to 2025
$7.1MRole of pro-inflammatory cytokines in drug induced osteonecrosis of the jawF30DE025172 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WILLIAMS, DRAKE WINSLOW · 2015 to 2019
$220kInvestigating role of maternal gut microbiome in microglia-neuron dynamics and development of somatosensory circuitsK99HD101680 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VUONG, HELEN · 2020 to 2021
$218kIntersections between the maternal microbiome, placental immunity, vasculature and fetal growthF31HD101270 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PRONOVOST, GEOFFREY NATHAN · 2019 to 2021
$79kFunctional Role of IL-6 in Fetal Brain Development and Abnormal BehaviorF31MH090749 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HSIAO, ELAINE · 2011 to 2012
$64kNICHD NIH HHS F31 HD101270NICHD NIH HHS K99 HD101680NIDCR NIH HHS F30 DE025172NIGMS NIH HHS K12 GM106996NIMH NIH HHS F31 MH090749
Abstract
'Dysbiosis' of the maternal gut microbiome, in response to challenges such as infection
Indexed as
MothersAnimalsAxonsBrainCerebral CortexComputer SimulationDysbiosisFemaleFetusGastrointestinal MicrobiomeMaleMiceMice, Inbred C57BLPregnancyPregnancy ComplicationsPrincipal Component Analysis
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.