ArticleNature2020
Light-driven post-translational installation of reactive protein side chains.
Abstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 177 citations in OpenAlex.
- Cyanamide-Induced Desulfhydration Enables Access to α,β-Dehydropeptides.Organic letters · 2026Article
- Recent advances in site-specific modifications of peptides and proteins.Chemical science · 2026Review
- Boron-Mediated Hydroalkylation of Unactivated Olefins: AnJournal of the American Chemical Society · 2026Article
- Mining lysine post-translational modification sites by integrating protein language model representations with structural context.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Bioorthogonal Photocatalytic Protein Labeling and Cross-Linking Enabled by Stabilized Ketyl Radicals.Journal of the American Chemical Society · 2025Article
- Desulfurative modification of cysteine residues in peptides and proteinsChemical science · 2025Article
- Visible Light Induced Mukaiyama Reagent Promoted Desulfurative Modification of Peptides and Proteins with Nucleotides.ACS central science · 2025Article
- A selenoxide for single-atom protein modification of tyrosine residues enabled by water-resistant chalcogen and hydrogen bonding.Nature chemistry · 2025Article
- Mild and Selective Trifluoromethylation of Peptides at Tryptophane Residues by a Water-Soluble Copper Complex with Redox-Active Ligands.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Advances in the chemical synthesis of human proteoforms.Science China. Life sciences · 2025Review
- Direct Editing of Cysteine to Electrophilic Alkyl Halides in Peptides.Journal of the American Chemical Society · 2025Article
- Thioglycoside functionalizationChemical communications (Cambridge, England) · 2025Article
- Photochemical synthesis of natural lipids in artificial and living cells.Nature communications · 2025Article
- Chemical Carbonylation of Arginine in Peptides and Proteins.Journal of the American Chemical Society · 2025Article
- Ligand-Enabled Selective Coupling of MIDA Boronates to Dehydroalanine-Containing Peptides and Proteins.Journal of the American Chemical Society · 2025Article
- Organic photoredox-catalyzed unimolecular PCET of benzylic alcohols.Chemical science · 2025Article
- Diversified Fluoroalkylation of Alkenes Using Quaternary Fluoroalkyl Alcohols as the Fluoroalkylating Reagents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Facile preparation of sulfonium peptide and protein probes for selective crosslinking of methyllysine readers.Chemical science · 2025Article
- Quantifying the ability of the CFBeilstein journal of organic chemistry · 2025Article
- Light-Driven Installation of Aminooxyhomolysine on Histones and Its Application for Synthesizing Stable and Site-Specific 3'-DNA-Histone Cross-Links.Bioconjugate chemistry · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 2 institutions in 2 countries.
Brian Josephson *Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Charlie Fehl *Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-6182-0879
Patrick G Isenegger *Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Simon NadalChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-0748-0284
Tom H WrightChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Adeline W J PohChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Ben J BowerChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Andrew M GiltrapChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Lifu ChenPhysical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Christopher Batchelor-McAuleyPhysical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Grace RoperChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-7198-0267
Oluwatobi ArisaChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Jeroen B I SapChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Akane KawamuraChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-1169-5082
Andrew J BaldwinChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-7579-8844
Shabaz MohammedChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-2640-9560
Richard G ComptonPhysical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Veronique GouverneurChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK. veronique.gouverneur@chem.ox.ac.uk.ORCID http://orcid.org/0000-0001-8638-5308
Benjamin G DavisChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK. ben.davis@rfi.ac.uk.ORCID http://orcid.org/0000-0002-5056-407X
University of Oxford · GBWayne State University · US
Funding
Cancer Research UK 18245Cancer Research UK 28285
Abstract
Post-translational modifications (PTMs) greatly expand the structures and functions of proteins in nature
Indexed as
LightAlanineBinding SitesCarbonEnzymesEstersHeLa CellsHumansHydrocarbons, FluorinatedIndicators and ReagentsOxidation-ReductionPhotochemical ProcessesProtein Interaction Domains and MotifsProtein Processing, Post-TranslationalProteinsAlanineCarbondehydroalaninedifluoromethaneEnzymesEstersHydrocarbons, FluorinatedIndicators and ReagentsProteins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.