Evidence map›Paper›PMID 32968253›Full record

ArticleNature2020

Zebrafish prrx1a mutants have normal hearts.

Federico Tessadori, Dennis E M de Bakker, Lindsey Barske, Nellie Nelson, Hermine A Algra, Sven Willekers, James T Nichols, J Gage Crump, Jeroen Bakkers

Abstract readLetterComment
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. The Interaction Between theInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Getting to the Heart of Left-Right Asymmetry: Contributions from the Zebrafish Model.Journal of cardiovascular development and disease · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Federico TessadoriHubrecht Institute-KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0001-9975-0546
Dennis E M de Bakker *Hubrecht Institute-KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands.
Lindsey Barske *Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, W. M. Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-1275-7978
Nellie NelsonDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, W. M. Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-3220-5601
Hermine A AlgraHubrecht Institute-KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands.
Sven WillekersHubrecht Institute-KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands.
James T NicholsDepartment of Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID http://orcid.org/0000-0002-7263-1704
J Gage CrumpDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, W. M. Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. gcrump@usc.edu.ORCID http://orcid.org/0000-0002-3209-0026
Jeroen BakkersHubrecht Institute-KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands. j.bakkers@hubrecht.eu.ORCID http://orcid.org/0000-0002-9418-0422

Funding

Progenitor Regulation in Craniofacial Development and RegenerationR35DE027550 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2017 to 2024
$8.0M
Molecular and Cellular Basis of CraniosynostosisR01DE026339 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2016 to 2025
$6.5M
Cell Fate Choices in the SkeletonR00DE024190 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI NICHOLS, JAMES TUCKER · 2017 to 2019
$887k
Prolonger progenitor maintenance sculpts the upper faceR00DE026239 · NIDCR · CINCINNATI CHILDRENS HOSP MED CTR · PI BARSKE, LINDSEY ANNE · 2019 to 2021
$744k
Modular control of jaw tendon specification by the Nr5a2 orphan nuclear receptorR21DE029656 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D, MERRILL, AMY E · 2020 to 2021
$649k
NIDCR NIH HHS R00 DE024190NIDCR NIH HHS R00 DE026239NIDCR NIH HHS R01 DE026339NIDCR NIH HHS R21 DE029656NIDCR NIH HHS R35 DE027550
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ZebrafishZebrafish ProteinsAnimalsOrganogenesisSignal TransductionZebrafish Proteins

Identifiers

PMID32968253
PMCPMC8191740

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.