Evidence map›Paper›PMID 32968106›Full record

ArticleScientific reports2020

Modulation of CYP2C9 activity and hydrogen peroxide production by cytochrome b

Javier Gómez-Tabales, Elena García-Martín, José A G Agúndez, Carlos Gutierrez-Merino

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Metabolic profiling analysis of cytochrome bMetabolomics : Official journal of the Metabolomic Society · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Ulcerative colitis: Timeline to a cure.World journal of gastroenterology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Regulating Effect of CytochromeMolecules (Basel, Switzerland) · 2022
    Article
  11. Review
  12. Article
  13. Structural Features of CytochromeInternational journal of molecular sciences · 2021
    Review
  14. PharmVar GeneFocus: CYP2C9.Clinical pharmacology and therapeutics · 2021
    Review
  15. Article
  16. Lack of Major Involvement of CommonFrontiers in pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Javier Gómez-TabalesUniversity Institute of Molecular Pathology Biomarkers, ARADyAL Instituto de Salud Carlos III, University of Extremadura, Cáceres, Spain.
Elena García-MartínUniversity Institute of Molecular Pathology Biomarkers, ARADyAL Instituto de Salud Carlos III, University of Extremadura, Cáceres, Spain. elenag@unex.es.
José A G AgúndezUniversity Institute of Molecular Pathology Biomarkers, ARADyAL Instituto de Salud Carlos III, University of Extremadura, Cáceres, Spain.
Carlos Gutierrez-MerinoUniversity Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006, Badajoz, Spain. carlosgm@unex.es.
Universidad de Extremadura · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytochromes P450 (CYP) play a major role in drug detoxification, and cytochrome b

Indexed as

Cytochrome P-450 CYP2C9Cytochromes b5HumansHydrogen PeroxideHydroxylationKineticsLiverMicrosomesOxidation-ReductionPeroxidesCYP2C9 protein, humanCytochrome P-450 CYP2C9Cytochromes b5Hydrogen PeroxidePeroxides

Identifiers

PMID32968106
PMCPMC7511354
OpenAlexW3088228529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.