ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
The Tubular Striatum.
Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Target-dependent routing of sensory information in the olfactory system.Communications biology · 2026Article
- Positive early-life olfactory memory is rooted in the olfactory bulb and triggers large-scale changes beyond the olfactory system.PLoS biology · 2026Article
- Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hedonic hotspot in rat olfactory tubercle: map for mu-opioid, orexin, and muscimol enhancement of sucrose 'liking'.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Rethinking the "olfactory" tubercle: a hedonic hotspot within ventral striatum.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Cariprazine modulates affective and social behaviors through ventral striatal islands of Calleja neurons.Current zoology · 2026Article
- Spatial segregation of piriform output neurons toward cognitive and emotional networks.PNAS nexus · 2026Article
- Hedonic hotspot in rat olfactory tubercle: map for mu-opioid, orexin, and muscimol enhancement of sucrose 'liking'.bioRxiv : the preprint server for biology · 2025Article
- A midbrain-to-ventral-striatum dopaminergic pathway orchestrates odor-guided insect predation in mice.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Directing negative emotional states through parallel genetically-distinct basolateral amygdala pathways to ventral striatum subregions.Molecular psychiatry · 2025Article
- SMUG1 DNA glycosylase modulates reward behaviour through regulation of olfactory receptor gene expression.Nucleic acids research · 2025Article
- Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior.Nature communications · 2025Article
- Differential potentiation of odor aversion and yawning by melanocortin 4 receptor signaling in distinct regions of the ventral striatum.Frontiers in neuroscience · 2025Article
- Laminar organization of the anterior olfactory nucleus-the interplay between neurogenesis timing and neuroblast migration.Frontiers in neuroscience · 2025Article
- Function of orexin-1 receptor signaling in the olfactory tubercle in odor-guided attraction and aversion.Communications biology · 2024Article
- Article
- Odor representation and coding by the mitral/tufted cells in the olfactory bulb.Journal of Zhejiang University. Science. B · 2024Review
- Structural Connectivity between Olfactory Tubercle and Ventrolateral Periaqueductal Gray Implicated in Human Feeding Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Connectivity of the olfactory tubercle: inputs, outputs, and their plasticity.Frontiers in neural circuits · 2024Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
In the mid-19th century, a misconception was born, which understandably persists in the minds of many neuroscientists today. The eminent scientist Albert von Kölliker named a tubular-shaped piece of tissue found in the brains of all mammals studied to date, the tuberculum olfactorium - or what is commonly known as the olfactory tubercle (OT). In doing this, Kölliker ascribed "olfactory" functions and an "olfactory" purpose to the OT. The OT has since been classified as one of several olfactory cortices. However, further investigations of OT functions, especially over the last decade, have provided evidence for roles of the OT beyond olfaction, including in learning, motivated behaviors, and even seeking of psychoactive drugs. Indeed, research to date suggests caution in assigning the OT with a purely olfactory role. Here, I build on previous research to synthesize a model wherein the OT, which may be more appropriately termed the "tubular striatum" (TuS), is a neural system in which sensory information derived from an organism's experiences is integrated with information about its motivational states to guide affective and behavioral responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.