Evidence map›Paper›PMID 32968014›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

DNA binding induces a

Aparna Unnikrishnan, Carlos Amero, Deepak Kumar Yadav, Kye Stachowski, Devante Potter, Mark P Foster

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Thermodynamics of Indirect Readout in Cre-bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Dynamics in Cre-loxP site-specific recombination.Current opinion in structural biology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Aparna UnnikrishnanDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210.ORCID 0000-0002-6668-8659
Carlos AmeroLaboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, 62209 Cuernavaca, Morelos, Mexico.ORCID 0000-0001-6300-0241
Deepak Kumar YadavDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210.ORCID 0000-0002-4555-3851
Kye StachowskiDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210.ORCID 0000-0003-2378-6651
Devante PotterDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210.
Mark P FosterDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210; foster.281@osu.edu.ORCID 0000-0001-9645-7491
The Ohio State University · USUniversidad Autónoma del Estado de Morelos · MX

Funding

TRD3 NMRbox: Bayesian AnalyticsP41GM111135 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HOCH, JEFFREY C · 2015 to 2024
$14.0M
Protein Dynamics in Site-Specific DNA RecombinationR01GM122432 · NIGMS · OHIO STATE UNIVERSITY · PI FOSTER, MARK P. · 2017 to 2020
$1.1M
NIGMS NIH HHS P41 GM111135NIGMS NIH HHS R01 GM122432
6 · The paper itself

Abstract

Mechanistic understanding of DNA recombination in the Cre

Indexed as

Binding SitesCrystallography, X-RayDNAIntegrasesModels, MolecularProtein BindingProtein ConformationProtein DomainsCre recombinaseDNAIntegrasesautoinhibitionCre recombinaseenzyme dynamicsparamagnetic relaxation enhancement (PRE) NMR

Identifiers

PMID32968014
PMCPMC7547242
OpenAlexW3088082995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.