Evidence map›Paper›PMID 32968012›Full record

ArticlemSphere2020

Immune Response Characterization after Controlled Infection with Lyophilized Shigella sonnei 53G.

Kristen A Clarkson, Robert W Frenck, Michelle Dickey, Akamol E Suvarnapunya, Lakshmi Chandrasekaran, Hailey P Weerts, Christopher D Heaney, Monica McNeal, Kate Detizio, Susan Parker and 5 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Antibodies Elicited by theFrontiers in immunology · 2021
    Trial
  4. Article
  5. Article
  6. Article
  7. mBio · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. International journal of molecular sciences · 2024
    Review
  12. Article
  13. Exploring Natural Immune Responses toOpen forum infectious diseases · 2024
    Article
  14. Oral immunization withmSphere · 2024
    Article
  15. Article
  16. Shigella-Controlled Human Infection Models: Current and Future Perspectives.Current topics in microbiology and immunology · 2024
    Review
  17. Review
  18. Development of themSphere · 2023
    Article
  19. A NovelmSphere · 2023
    Article
  20. Functional assays to evaluate antibody-mediated responses againstFrontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Kristen A ClarksonDepartment of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Robert W FrenckCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0002-2336-526X
Michelle DickeyCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Akamol E SuvarnapunyaDepartment of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Lakshmi ChandrasekaranDepartment of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Hailey P WeertsDepartment of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Christopher D HeaneyJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Monica McNealCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Kate DetizioNaval Medical Research Center, Silver Spring, Maryland, USA.
Susan ParkerCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Amy HoeperCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
August L BourgeoisPATH, Washington, DC, USA.
Chad K PorterNaval Medical Research Center, Silver Spring, Maryland, USA.
Malabi M VenkatesanDepartment of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Robert W KaminskiDepartment of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA Robert.W.Kaminski.civ@mail.mil.ORCID 0000-0002-4015-5694
Walter Reed Army Institute of Research · USCincinnati Children's Hospital Medical Center · USNaval Medical Research Command · USJohns Hopkins University · USProgram for Appropriate Technology in Health · US

Funding

Antimicrobial resistant E. coli before and after California Senate bill 27 (ARES): a natural experimentR01AI130066 · NIAID · KAISER FOUNDATION RESEARCH INSTITUTE · PI TARTOF, SARA · 2017 to 2021
$3.8M
Arsenic and immune response to influenza vaccination in pregnant women and newbornsR01ES026973 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HEANEY, CHRISTOPHER D, LABRIQUE, ALAIN BERNARD · 2017 to 2021
$3.6M
Multiplex oral fluid antibody assay for arbovirus diagnosis, surveillance and preventionR21AI139784 · NIAID · JOHNS HOPKINS UNIVERSITY · PI COLLINS, MATTHEW, HEANEY, CHRISTOPHER D · 2018 to 2019
$459k
Non-Invasive Zoonotic Pathogen Exposure & Outcome BiomarkersK01OH010193 · OH · JOHNS HOPKINS UNIVERSITY · PI HEANEY, CHRISTOPHER D · 2012 to 2014
$324k
Development of a point of care lateral flow diagnostic to test for acute and past hepatitis E (HEV) in salivaR43AI141265 · NIAID · NANOCOMPOSIX, INC. · PI BALDWIN, RICHARD KIMO, PISANIC, NORA · 2018 to 2018
$225k
National Science Foundation 1316318NIAID NIH HHS R01 AI130066NIAID NIH HHS R21 AI139784NIAID NIH HHS R43 AI141265NIEHS NIH HHS R01 ES026973NIOSH CDC HHS K01 OH010193NIOSH CDC HHS T42 OH008428
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunologic MemoryAdolescentAdultAntibodies, BacterialBacterial VaccinesB-LymphocytesDysentery, BacillaryFecesFemaleFreeze DryingHumansImmunoglobulin AImmunoglobulin GLipopolysaccharidesMaleMiddle AgedAntibodies, BacterialBacterial VaccinesImmunoglobulin AImmunoglobulin GLipopolysaccharidesantibodycontrolled human infection modelgut hominggut-homing responsesimmunogenicityimmunological memoryShigellaShigella sonnei

Identifiers

PMID32968012
PMCPMC7568644
OpenAlexW3088918855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.