Evidence map›Paper›PMID 32967958›Full record

ArticleJournal of virology2020

HIV Infection and Persistence in Pulmonary Mucosal Double Negative T Cells

Oussama Meziane, Syim Salahuddin, Tram N Q Pham, Omar Farnos, Amélie Pagliuzza, Ron Olivenstein, Elaine Thomson, Yulia Alexandrova, Marianna Orlova, Erwin Schurr and 6 more

Abstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Blocking activation of CD4Clinical immunology (Orlando, Fla.) · 2023
    Article
  9. CD73: Friend or Foe in Lung Injury.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Oussama Meziane *Infectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Syim Salahuddin *Infectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Tram N Q PhamInstitut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada.
Omar FarnosDepartment of Biological Sciences, Université du Québec à Montréal, Montreal, Quebec, Canada.
Amélie PagliuzzaCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Ron OlivensteinDivision of Respirology, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Elaine ThomsonInfectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Yulia AlexandrovaInfectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Marianna OrlovaInfectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Erwin SchurrInfectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Petronela AncutaCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Élie HaddadDépartement de microbiologie, infectiologie et immunologie, Université de Montréal, Montreal, Quebec, Canada.
Nicolas ChomontCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Eric A CohenInstitut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada.ORCID 0000-0003-1269-3791
Mohammad-Ali Jenabian *Department of Biological Sciences, Université du Québec à Montréal, Montreal, Quebec, Canada jenabian.mohammed-ali@uquam.ca cecilia.costiniuk@mcgill.ca.ORCID 0000-0003-4321-9777
Cecilia T Costiniuk *Infectious Diseases and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada jenabian.mohammed-ali@uquam.ca cecilia.costiniuk@mcgill.ca.ORCID 0000-0002-4547-714X

Funding

CIHR 153082CIHR HB2164064
6 · The paper itself

Abstract

The lungs are relatively unexplored anatomical human immunodeficiency virus (HIV) reservoirs in the antiretroviral therapy (ART) era. Double negative (DN) T cells are a subset of T cells that lack expression of CD4 and CD8 (CD4

Indexed as

AnimalsBronchoalveolar Lavage FluidCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHIV InfectionsHumansLungProgrammed Cell Death 1 ReceptorReceptors, CCR6Receptors, CXCR3T-LymphocytesCCR6 protein, humanCXCR3 protein, humanPDCD1 protein, humanProgrammed Cell Death 1 ReceptorReceptors, CCR6Receptors, CXCR3double negative (DN) T cellsHIV persistencelungspulmonary mucosal immunityT-cell immunity

Identifiers

PMID32967958
PMCPMC7925170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.