Evidence map›Paper›PMID 32967724›Full record

ArticleParasites & vectors2020

Molluscicidal and parasiticidal activities of Eryngium triquetrum essential oil on Schistosoma mansoni and its intermediate snail host Biomphalaria glabrata, a double impact.

Ronaldo de Carvalho Augusto, Nadjiya Merad, Anne Rognon, Benjamin Gourbal, Cédric Bertrand, Nassim Djabou, David Duval

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Analysis ofBiochemistry and biophysics reports · 2024
    Article
  3. Article
  4. Review
  5. Molluscicidal and Cercaricidal Effects ofMolecules (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ronaldo de Carvalho AugustoUniversity Perpignan Via Domitia, IHPE, UMR 5244, CNRS, IFREMER, Perpignan, France.
Nadjiya MeradFaculté des Sciences, Département de Chimie, Université de Tlemcen, Laboratoire COSNA, Tlemcen, Algeria.
Anne RognonUniversity Perpignan Via Domitia, IHPE, UMR 5244, CNRS, IFREMER, Perpignan, France.
Benjamin GourbalUniversity Perpignan Via Domitia, IHPE, UMR 5244, CNRS, IFREMER, Perpignan, France.
Cédric BertrandEPHE-UPVD-CNRS, USR 3278 CRIOBE, Université de Perpignan, Perpignan, France.
Nassim DjabouFaculté des Sciences, Département de Chimie, Université de Tlemcen, Laboratoire COSNA, Tlemcen, Algeria. nassim.djabou@mail.univ-tlemcen.dz.
David DuvalUniversity Perpignan Via Domitia, IHPE, UMR 5244, CNRS, IFREMER, Perpignan, France. david.duval@univ-perp.fr.ORCID http://orcid.org/0000-0001-6933-3354
Centre National de la Recherche Scientifique · FRUniversity of Abou Bekr Belkaïd · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFreshwater snails are the intermediate hosts of a large variety of trematode flukes such as Schistosoma mansoni responsible for one of the most important parasitic diseases caused by helminths, affecting 67 million people worldwide. Recently, the WHO Global Vector Control Response 2017-2030 (GVCR) programme reinforced its message for safer molluscicides as part of required strategies to strengthen vector control worldwide. Here, we present the essential oil from Eryngium triquetrum as a powerful product with molluscicide and parasiticide effect against S. mansoni and the snail intermediate host Biomphalaria glabrata.

methodsIn the present study, we describe using several experimental approaches, the chemical composition of E. triquetrum essential oil extract and its biological effects against the snail B. glabrata and its parasite S. mansoni. Vector and the free-swimming larval stages of the parasite were exposed to different oil concentrations to determine the lethal concentration required to produce a mortality of 50% (LC

resultsThe major chemical component found in E. triquetrum oil determined by GC-FID and GC/MS analyses is an aliphatic polyacetylene molecule, the falcarinol with 86.9-93.1% of the total composition. The LC

conclusionsEssential oil extracted from E. triquetrum and falcarinol must be considered as a promising product for the development of new interventions for schistosomiasis control and could proceed to be tested on Phase II according to the WHO requirements.

Indexed as

AnimalsAnthelminticsBiomphalariaDisease VectorsEryngiumHumansLethal Dose 50MolluscacidesOils, VolatilePlant ExtractsPlant OilsSchistosoma mansoniSchistosomiasis mansoniAnthelminticsMolluscacidesOils, VolatilePlant ExtractsPlant OilsBiomphalaria glabrataEryngium triquetrumMolluscicideOilParasiticideSchistosoma mansoni

Identifiers

PMID32967724
PMCPMC7513307
OpenAlexW3088396028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.