Evidence map›Paper›PMID 32967301›Full record

ArticleInternational journal of environmental research and public health2020

Prenatal Maternal Cortisol Levels and Infant Birth Weight in a Predominately Low-Income Hispanic Cohort.

Alicia K Peterson, Claudia M. Toledo-Corral, Thomas A Chavez, Christine H Naya, Mark Johnson, Sandrah P Eckel, Deborah Lerner, Brendan H Grubbs, Shohreh F Farzan, Genevieve F Dunton and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alicia K PetersonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Claudia M. Toledo-CorralDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.ORCID 0000-0002-1228-9070
Thomas A ChavezDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Christine H NayaDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.ORCID 0000-0002-1575-6308
Mark JohnsonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Sandrah P EckelDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Deborah LernerEisner Health, Los Angeles, CA 90015, USA.
Brendan H GrubbsDepartment of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Shohreh F FarzanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Genevieve F DuntonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Theresa M BastainDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Carrie V BretonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
University of Southern California · US

Funding

Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4M
Project 3: Maternal Exposure to Environmental Hazards and Psychosocial Stressors and Postpartum Allostatic LoadP50MD015705 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M · 2020 to 2024
$8.1M
Project 2: Environmental Exposures, Stress, and Maternal Pregnancy-Related Weight OutcomesP50ES026086 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M · 2015 to 2019
$3.7M
NIEHS NIH HHS P50 ES026086NIH HHS UH3 OD023287NIMHD NIH HHS P50 MD015705
6 · The paper itself

Abstract

Infant birth weight influences numerous health outcomes throughout the life course including childhood obesity and metabolic morbidities. Maternal experience of stress, both before and during pregnancy, has been hypothesized to influence fetal growth and birth outcomes. However, these associations currently are not fully understood, due to conflicting results in the published literature. Salivary cortisol is often used as a biological biomarker to assess the diurnal pattern of the hypothalamic-pituitary-adrenal axis (HPA-axis) functioning. Cortisol metrics include both the total cortisol concentration secreted during waking hours, reflected by the area under the curve (AUC), and cortisol dynamics, which include the diurnal cortisol slope (DCS) and the cortisol awakening response (CAR). This study examined the association of these cortisol metrics measured during the third trimester of pregnancy and infant birth weight among 240 mother-infant dyads participating in the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) pregnancy cohort study, which is predominately comprised of Hispanic low-income women. There were no significant associations with the maternal biological stress response and infant birth weight in this study. More research is needed in larger studies to better understand how the biological stress response influences birth weight in populations facing health disparities.

Indexed as

Birth WeightHydrocortisonePremature BirthAdultCesarean SectionCohort StudiesFemaleHispanic or LatinoHumansHypothalamo-Hypophyseal SystemIncomeInfant, NewbornPituitary-Adrenal SystemPregnancySalivaStress, PsychologicalHydrocortisonebirth weightcortisolpregnancystress

Identifiers

PMID32967301
PMCPMC7559007
OpenAlexW3087224523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.