Evidence map›Paper›PMID 32967202›Full record

ArticleJournal of clinical medicine2020

Monocyte Chemoattractant Protein-1 Is an Independent Predictor of Coronary Artery Ectasia in Patients with Acute Coronary Syndrome.

Juan Antonio Franco-Peláez, Roberto Martín-Reyes, Ana María Pello-Lázaro, Álvaro Aceña, Óscar Lorenzo, José Luis Martín-Ventura, Luis Blanco-Colio, María Luisa González-Casaus, Ignacio Hernández-González, Rocío Carda and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Juan Antonio Franco-PeláezDepartment of Cardiology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0001-5360-7066
Roberto Martín-ReyesDepartment of Cardiology, Hospital La Luz, 28003 Madrid, Spain.
Ana María Pello-LázaroDepartment of Cardiology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-5699-3422
Álvaro AceñaDepartment of Cardiology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, 28040 Madrid, Spain.
Óscar LorenzoDepartment of Medicine, Autónoma University, 28049 Madrid, Spain.
José Luis Martín-VenturaDepartment of Medicine, Autónoma University, 28049 Madrid, Spain.
Luis Blanco-ColioLaboratory of Vascular Pathology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-1560-6609
María Luisa González-CasausLaboratory of Nephrology and Mineral Metabolism, Hospital Gómez-Ulla, 28047 Madrid, Spain.
Ignacio Hernández-GonzálezDepartment of Cardiology, Hospital Universitario Río Hortega, 47012 Valladolid, Spain.
Rocío CardaDepartment of Cardiology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, 28040 Madrid, Spain.
María Luisa Martín-MariscalDepartment of Cardiology, Hospital Ruber Juan Bravo, 28006 Madrid, Spain.
Jesús EgidoDepartment of Medicine, Autónoma University, 28049 Madrid, Spain.
José TuñónDepartment of Cardiology, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-1373-0999
Hospital Universitario Fundación Jiménez Díaz · ESCentro de Investigación Biomédica en Red · ESCentro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ESHospital Central de la Defensa Gómez Ulla · ESHospital La Luz · ESHospital Ruber Internacional · ESHospital Universitario Río Hortega · ES

Funding

Instituto de Investigaciones Sanitarias PI05/0451, PI05/1497, PI05/52475, PI05/1043, PS09/01405, and PI10/00072, PI14/01567, PI17/01615Instituto de Salud Carlos III FEDER RD09/0076/ 00101RECAVA RD06/0014/0035
6 · The paper itself

Abstract

Our purpose was to assess a possible association of inflammatory, lipid and mineral metabolism biomarkers with coronary artery ectasia (CAE) and to determine a possible association of this with acute atherotrombotic events (AAT). We studied 270 patients who underwent coronary angiography during an acute coronary syndrome 6 months before. Plasma levels of several biomarkers were assessed, and patients were followed during a median of 5.35 (3.88-6.65) years. Two interventional cardiologists reviewed the coronary angiograms, diagnosing CAE according to previously published criteria in 23 patients (8.5%). Multivariate binary logistic regression analysis was used to search for independent predictors of CAE. Multivariate analysis revealed that, aside from gender and a diagnosis of dyslipidemia, only monocyte chemoattractant protein-1 (MCP-1) (OR = 2.25, 95%CI = (1.35-3.76) for each increase of 100 pg/mL,

Indexed as

acute atherotrombotic eventscoronary artery diseasecoronary artery ectasialow-density lipoproteinmonocyte chemoattractant protein-1

Identifiers

PMID32967202
PMCPMC7563376
OpenAlexW3087671805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.