Evidence map›Paper›PMID 32967189›Full record

ArticleSensors (Basel, Switzerland)2020

Identification and Quantitative Determination of Lactate Using Optical Spectroscopy-Towards a Noninvasive Tool for Early Recognition of Sepsis.

Karthik Budidha, Mohammad Mamouei, Nystha Baishya, Meha Qassem, Pankaj Vadgama, Panayiotis A Kyriacou

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karthik BudidhaResearch Centre for Biomedical Engineering, School of Engineering and Mathematical Sciences, University of London, Northampton Square, London EC1V 0HB, UK.
Mohammad MamoueiResearch Centre for Biomedical Engineering, School of Engineering and Mathematical Sciences, University of London, Northampton Square, London EC1V 0HB, UK.
Nystha BaishyaResearch Centre for Biomedical Engineering, School of Engineering and Mathematical Sciences, University of London, Northampton Square, London EC1V 0HB, UK.ORCID 0000-0002-2231-6132
Meha QassemResearch Centre for Biomedical Engineering, School of Engineering and Mathematical Sciences, University of London, Northampton Square, London EC1V 0HB, UK.
Pankaj VadgamaInterdisciplinary Research Centre (IRC) in Biomedical Materials, Queen Mary University of London (QMUL), Mile End Road, London E1 4NS, UK.ORCID 0000-0001-6696-6017
Panayiotis A KyriacouResearch Centre for Biomedical Engineering, School of Engineering and Mathematical Sciences, University of London, Northampton Square, London EC1V 0HB, UK.ORCID 0000-0002-2868-485X
University of London · GBQueen Mary University of London · GB

Funding

Engineering and Physical Sciences Research Council EP/R003750/1
6 · The paper itself

Abstract

Uninterrupted monitoring of serum lactate levels is a prerequisite in the critical care of patients prone to sepsis, cardiogenic shock, cardiac arrest, or severe lung disease. Yet there exists no device to continuously measure blood lactate in clinical practice. Optical spectroscopy together with multivariate analysis is proposed as a viable noninvasive tool for estimation of lactate in blood. As an initial step towards this goal, we inspected the plausibility of predicting the concentration of sodium lactate (NaLac) from the UV/visible, near-infrared (NIR), and mid-infrared (MIR) spectra of 37 isotonic phosphate-buffered saline (PBS) samples containing NaLac ranging from 0 to 20 mmol/L. UV/visible (300-800 nm) and NIR (800-2600 nm) spectra of PBS samples were collected using the PerkinElmer Lambda 1050 dual-beam spectrophotometer, while MIR (4000-500 cm

Indexed as

Spectroscopy, Near-InfraredHumansLactic AcidLeast-Squares AnalysisMultivariate AnalysisSepsisLactic Acidblood lactatemid-infrared spectranear infrared spectroscopysepsisUV/visible spectra

Identifiers

PMID32967189
PMCPMC7570541
OpenAlexW3087752148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.