Evidence map›Paper›PMID 32967147›Full record

ArticleGenes2020

Gene Polymorphisms of

Elina Tenhu, Johanna Teräsjärvi, Manuel Leite Cruzeiro, Okko Savonius, Emilie Rugemalira, Irmeli Roine, Qiushui He, Tuula Pelkonen

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Elina TenhuInstitute of Biomedicine, Research Center of Infections and Immunity, University of Turku, 20520 Turku, Finland.
Johanna TeräsjärviInstitute of Biomedicine, Research Center of Infections and Immunity, University of Turku, 20520 Turku, Finland.
Manuel Leite CruzeiroHospital Pediátrico David Bernardino, Luanda 00000, Angola.
Okko SavoniusChildren's Hospital, Pediatric Research Center, University of Helsinki, Helsinki University Hospital, 00029 Helsinki, Finland.
Emilie RugemaliraChildren's Hospital, Pediatric Research Center, University of Helsinki, Helsinki University Hospital, 00029 Helsinki, Finland.
Irmeli RoineFaculty of Medicine, University Diego Portales, Santiago 8370109, Chile.ORCID 0000-0003-0020-361X
Qiushui HeInstitute of Biomedicine, Research Center of Infections and Immunity, University of Turku, 20520 Turku, Finland.
Tuula PelkonenHospital Pediátrico David Bernardino, Luanda 00000, Angola.ORCID 0000-0002-7688-9059
University of Helsinki · FIUniversity of Turku · FIClínica Sagrada Esperança · AOUniversidad Diego Portales · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial meningitis (BM) is a severe disease caused by various bacterial pathogens. Toll-like receptors (TLRs) protect humans from invading pathogens. In this study, we determined whether single nucleotide polymorphisms (SNPs) of

Indexed as

AdolescentChildChild, PreschoolFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHaemophilus InfectionsHaemophilus influenzaeHumansInfantInfant, NewbornMaleMeningitis, HaemophilusNeisseria meningitidisPolymorphism, Single NucleotideTLR4 protein, humanTLR9 protein, humanToll-Like Receptor 4Toll-Like Receptor 9Angolachildrengene polymorphismsHaemophilus influenzaeHRMAmeningitisTLR4TLR9

Identifiers

PMID32967147
PMCPMC7564843
OpenAlexW3087131529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.