ArticleAntibiotics (Basel, Switzerland)2020
Figainin 1, a Novel Amphibian Skin Peptide with Antimicrobial and Antiproliferative Properties.
Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Natural and Synthetic AMPs from Latin America across Diversity Engineering and Applications.ACS infectious diseases · 2026Review
- Frog Skin Peptides: Nature's Dual-Action Weapons Against Infection and Cancer.Antibiotics (Basel, Switzerland) · 2026Review
- PEPAD: A Promising Therapeutic Approach for the Treatment of Murine Melanoma (B16F10-Nex2).Pharmaceuticals (Basel, Switzerland) · 2025Article
- Investigating the Antimicrobial Activity of Anuran Toxins.Microorganisms · 2025Review
- The Therapeutic Potential of Antimicrobial Peptides Isolated from the Skin Secretions of Anurans of the GenusToxins · 2025Review
- Immunohistochemical Characterization of Langerhans Cells in the Skin of Three Amphibian Species.Biology · 2024Article
- Influence of Fatty Acid Modification on the Anticancer Activity of the Antimicrobial Peptide Figainin 1.ACS omega · 2023Article
- Amphibian-Derived Natural Anticancer Peptides and Proteins: Mechanism of Action, Application Strategies, and Prospects.International journal of molecular sciences · 2023Review
- Purification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator TreefrogAntibiotics (Basel, Switzerland) · 2023Article
- Antimicrobial Peptides (AMPs): Potential Therapeutic Strategy against Trypanosomiases?Biomolecules · 2023Review
- Purification and Biological Properties of Raniseptins-3 and -6, Two Antimicrobial Peptides fromBiomolecules · 2023Article
- The Complex Bridge between Aquatic and Terrestrial Life: Skin Changes during Development of Amphibians.Journal of developmental biology · 2023Review
- Article
- Development of Antimicrobial Peptides from Amphibians.Antibiotics (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amphibian skin secretions are abundant in bioactive compounds, especially antimicrobial peptides. These molecules are generally cationic and rich in hydrophobic amino acids, have an amphipathic structure and adopt an α-helical conformation when in contact with microorganisms membranes. In this work, we purified and characterized Figainin 1, a novel antimicrobial and antiproliferative peptide from the cutaneous secretion of the frog
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.