ArticleUrology2021
Association of Surgical Delay and Overall Survival in Patients With T2 Renal Masses: Implications for Critical Clinical Decision-making During the COVID-19 Pandemic.
Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Racial/ethnic differences in time to nephrectomy and its association with cancer-specific mortality in localized renal cell carcinoma.International urology and nephrology · 2026Article
- Temporal trends and sociodemographic determinants of time to nephrectomy in localized renal cell cancer.International urology and nephrology · 2026Article
- Oncologic outcomes of surgical delay by interval and tumor size in T1b-T2aN0M0 renal cell carcinoma.World journal of surgical oncology · 2025Article
- Neighborhood social vulnerability and disparities in time to kidney cancer surgical treatment and survival in Arizona.Cancer medicine · 2024Article
- The Impact of the COVID-19 Pandemic on Cancer Mortality in Pennsylvania: A Retrospective Study with Geospatial Analysis.Cancers · 2023Article
- Delay in Regular Visits of Chronic Disease Patients and Its Associated Factors during the COVID-19 Pandemic.Iranian journal of medical sciences · 2023Article
- Surgical Delay Increases the Perioperative Blood Transfusion Rate In Percutaneous Nephrolithotomy.Sisli Etfal Hastanesi tip bulteni · 2023Article
- An Analysis of Google Trends During COVID-19: Determining Public Urological Cancer Concerns.Cureus · 2022Article
- Determinants of COVID-19 Outcome as Predictors of Delayed Healthcare Services among Adults ≥50 Years during the Pandemic: 2006-2020 Health and Retirement Study.International journal of environmental research and public health · 2022Article
- Impact of COVID-19 Pandemic on Non-Melanoma Skin Cancer's Tumor Burden and Care: a Multi-Center Study Based in Northern Italy.Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2022Article
- The Impact of the COVID-19 Pandemic on Cancer Care and Health-Related Quality of Life of Non-Hispanic Black/African American, Hispanic/Latina and Non-Hispanic White Women Diagnosed with Breast Cancer in the U.S.: A Mixed-Methods Study Protocol.International journal of environmental research and public health · 2021Article
- Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea.Critical reviews in oncology/hematology · 2021Review
- Assessment of Prostate Cancer Treatment Among Black and White Patients During the COVID-19 Pandemic.JAMA oncology · 2021Article
- Racial and Ethnic Disparities in Preoperative Surgical Wait Time and Renal Cell Carcinoma Tumor Characteristics.Healthcare (Basel, Switzerland) · 2021Article
- Changes in Surgical Admissions and Outcomes During and After the COVID-19 Pandemic: An Exploration of the Australian and New Zealand Audit of Surgical Mortality (ANZASM).ANZ journal of surgeryArticle
- Impact of the COVID-19 pandemic on primary brain tumor incidence and management: Decisions that went right.Neuro-oncology advancesArticle
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo test for an association between surgical delay and overall survival (OS) for patients with T2 renal masses. Many health care systems are balancing resources to manage the current COVID-19 pandemic, which may result in surgical delay for patients with large renal masses.
methodsUsing Cox proportional hazard models, we analyzed data from the National Cancer Database for patients undergoing extirpative surgery for clinical T2N0M0 renal masses between 2004 and 2015. Study outcomes were to assess for an association between surgical delay with OS and pathologic stage.
resultsWe identified 11,848 patients who underwent extirpative surgery for clinical T2 renal masses. Compared with patients undergoing surgery within 2 months of diagnosis, we found worse OS for patients with a surgical delay of 3-4 months (hazard ratio [HR] 1.12, 95% confidence interval [CI] 1.00-1.25) or 5-6 months (HR 1.51, 95% CI 1.19-1.91). Considering only healthy patients with Charlson Comorbidity Index = 0, worse OS was associated with surgical delay of 5-6 months (HR 1.68, 95% CI 1.21-2.34, P= .002) but not 3-4 months (HR 1.08, 95% CI 0.93-1.26, P = 309). Pathologic stage (pT or pN) was not associated with surgical delay.
conclusionProlonged surgical delay (5-6 months) for patients with T2 renal tumors appears to have a negative impact on OS while shorter surgical delay (3-4 months) was not associated with worse OS in healthy patients. The data presented in this study may help patients and providers to weigh the risk of surgical delay versus the risk of iatrogenic SARS-CoV-2 exposure during resurgent waves of the COVID-19 pandemic.
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