Evidence map›Paper›PMID 32966747›Full record

ArticleACS synthetic biology2020

Leveraging Oxidative Stress to Regulate Redox Balance-Based,

Sarah Maxel, Edward King, Yulai Zhang, Ray Luo, Han Li

Open access · greenAbstract read
In one paragraph

Article in ACS synthetic biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Directed evolution of hydrocarbon-producing enzymes.Biotechnology for biofuels and bioproducts · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah Maxel
Edward King
Yulai Zhang
University of California, Irvine · US

Funding

Multi-scaled Modeling of Electrostatic and Polarization Effects in BiomoleculesR35GM130367 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI RAY LUO · 2019 to 2026
$3.0M
Engineering an unnatural redox cofactor (uRedox) system for efficient biosynthesis of medicinesDP2GM137427 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LI, HAN · 2019 to 2022
$2.4M
NIGMS NIH HHS DP2 GM137427NIGMS NIH HHS R35 GM130367
6 · The paper itself

Abstract

Directed evolution methods based on high-throughput growth selection enable efficient discovery of enzymes with improved function

Indexed as

AcenaphthenesBacterial ProteinsCatalysisCytochrome P-450 Enzyme SystemDirected Molecular EvolutionEnvironmental PollutantsEscherichia coliMutagenesis, Site-DirectedOxidation-ReductionOxidative StressOxygenasesProtein EngineeringReactive Oxygen SpeciesacenaphtheneAcenaphthenesBacterial ProteinsCytochrome P-450 Enzyme SystemEnvironmental PollutantsOxygenasesReactive Oxygen Speciescouplingdirected evolutiongrowth selectionhigh-throughputoxidative stressP450-BM3

Identifiers

PMID32966747
PMCPMC10441625
OpenAlexW3089326444

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.