Evidence map›Paper›PMID 32966690›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2020

Myocardial work in hypertensive patients with and without diabetes: An echocardiographic study.

Marijana Tadic, Cesare Cuspidi, Biljana Pencic, Guido Grassi, Vera Celic

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In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Marijana TadicDepartment of Cardiology, University Hospital "Dr. Dragisa Misovic - Dedinje", Belgrade, Serbia.ORCID 0000-0002-6235-5152
Cesare CuspidiDepartment of Medicine and Surgery, University Milano-Bicocca, Milano, Italy.
Biljana PencicDepartment of Cardiology, University Hospital "Dr. Dragisa Misovic - Dedinje", Belgrade, Serbia.
Guido GrassiDepartment of Medicine and Surgery, University Milano-Bicocca, Milano, Italy.
Vera CelicDepartment of Cardiology, University Hospital "Dr. Dragisa Misovic - Dedinje", Belgrade, Serbia.
University Hospital Center Dr Dragiša Mišović · RSIRCCS Istituto Auxologico Italiano · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to investigate myocardial performance using pressure-strain loops in hypertensive patients with and without type 2 diabetes mellitus (DM). This cross-sectional study included 165 subjects (55 controls, 60 hypertensive patients without DM, and 50 hypertensive patients with DM) who underwent complete two-dimensional echocardiographic examination (2DE) including two-dimensional speckle-tracking echocardiography. Pressure-strain curve was used to determine global myocardial work index, constructive work, wasted work, and work efficiency in all study participants. Left ventricular (LV) longitudinal and circumferential strains gradually reduced from controls throughout hypertensive subjects to patients with DM and hypertension. Global myocardial work index gradually increased from controls, throughout hypertensive patients to subjects with hypertension and DM (1887 ± 289 vs 2073 ± 311 vs 2144 ± 345 mm Hg%, P = .001). Constructive work increased in the same direction (2040 ± 319 vs 2197 ± 344 vs 2355 ± 379 mm Hg%, P < .001). Work efficiency and wasted work did not differ between three observed groups. Glycosylated hemoglobin and systolic blood pressure were associated with global myocardial work and constructive work independently of age, body mass index, LV structural and functional parameters in all hypertensive participants. In conclusion, pressure-strain curve showed that myocardial work was significantly affected by hypertension and diabetes. Diabetes demonstrated an additional negative effect on myocardial work in hypertensive patients.

Indexed as

HypertensionCross-Sectional StudiesDiabetes Mellitus, Type 2EchocardiographyHeart VentriclesHumansVentricular Dysfunction, Leftdiabeteshypertensionleft ventriclemyocardial work

Identifiers

PMID32966690
PMCPMC8029739
OpenAlexW3088877883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.