Evidence map›Paper›PMID 32966073›Full record

ArticleJournal of the American Chemical Society2020

Radical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover.

Adrien Pagnier, Hao Yang, Richard J Jodts, Christopher D James, Eric M Shepard, Stella Impano, William E Broderick, Brian M Hoffman, Joan B Broderick

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. The radical SAM enzyme EpeE exhibits distinct site reactivity during the biosynthesis of the RiPP natural product epipeptide.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Journal of the American Chemical Society · 2022
    Article
  7. The BJournal of inorganic biochemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Adrien PagnierDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana. 59717, United States.ORCID 0000-0002-1951-2415
Hao YangDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0001-7229-0957
Richard J JodtsDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0001-7467-492X
Christopher D JamesDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-6207-6380
Eric M ShepardDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana. 59717, United States.
Stella ImpanoDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana. 59717, United States.ORCID 0000-0002-8251-9441
William E BroderickDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana. 59717, United States.ORCID 0000-0001-5782-7322
Brian M HoffmanDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-3100-0746
Joan B BroderickDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana. 59717, United States.ORCID 0000-0001-7057-9124
Montana State University · USNorthwestern University · US

Funding

Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7M
Iron-Sulfur Clusters in Biological Radical GenerationR01GM054608 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI BRODERICK, JOAN B · 2001 to 2018
$4.7M
Molecular Biophysics Training Program at Northwestern UniversityT32GM008382 · NIGMS · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 1990 to 2020
$4.3M
Radical SAM Enzymes: Radical Mechanisms Central to BiologyR35GM131889 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Joan B Broderick · 2019 to 2026
$3.0M
SPECTROSCOPIC STUDIES OF PYRUVATE FORMATE LYASE ACTIVASER29GM054608 · NIGMS · MICHIGAN STATE UNIVERSITY · PI BRODERICK, JOAN B. · 1997 to 2000
$102k
NIGMS NIH HHS R01 GM054608NIGMS NIH HHS R01 GM111097NIGMS NIH HHS R29 GM054608NIGMS NIH HHS R35 GM131889NIGMS NIH HHS T32 GM008382
6 · The paper itself

Abstract

Spore photoproduct lyase is a radical

Indexed as

Catalytic DomainDensity Functional TheoryDeoxyadenosinesElectron Spin Resonance SpectroscopyFree RadicalsGeobacillusIron-Sulfur ProteinsModels, MolecularProteinsS-AdenosylmethionineDeoxyadenosinesFree RadicalsIron-Sulfur ProteinsProteinsS-Adenosylmethioninespore photoproduct lyase

Identifiers

PMID32966073
PMCPMC7730139
OpenAlexW3088807463

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.