Evidence map›Paper›PMID 32965749›Full record

ArticleMolecular systems biology2020

Implications of initial physiological conditions for bacterial adaptation to changing environments.

Matthias Heinemann, Markus Basan, Uwe Sauer

Open access · goldAbstract readLetterComment
In one paragraph

Article in Molecular systems biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Matthias HeinemannMolecular Systems Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-5512-9077
Markus BasanInstitute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Uwe SauerInstitute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-5923-0770
ETH Zurich · CHHarvard University · USUniversity of Groningen · NL

Funding

Elucidating physiology of dormant bacteria to combat antibiotic persistenceR35GM137895 · NIGMS · HARVARD MEDICAL SCHOOL · PI Markus Thomas Basan · 2020 to 2026
$3.2M
NIGMS NIH HHS R35 GM137895
6 · The paper itself

Abstract

This piece discusses how the different observations of two independent studies (Kotte et al, 2014; Basan et al, 2020), regarding population-level heterogeneity and lag times during diauxic shift, can be largely explained by different experimental protocols.

Indexed as

BacteriaCarbonAdaptation, PhysiologicalEscherichia coliCarbon

Identifiers

PMID32965749
PMCPMC7510564
OpenAlexW3088131780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.