Evidence map›Paper›PMID 32965723›Full record

ArticleAlcoholism, clinical and experimental research2020

Latent Profile Analysis of Heavy Episodic Drinking in Emerging Adults: A Reinforcer Pathology Approach.

Meenu Minhas, Assaf Oshri, Michael Amlung, Ashley Dennhardt, Mark Ferro, Jillian Halladay, Catharine Munn, Jalie Tucker, James Murphy, James MacKillop

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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  7. Reward deprivation is associated with elevated alcohol demand in emerging adults.Journal of the experimental analysis of behavior · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Meenu MinhasFrom the, Peter Boris Centre for Addictions Research, (MM, MA, CM, JMa), St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada.ORCID 0000-0001-6741-3940
Assaf OshriDepartment of Human Development and Family Sciences, (AO), University of Georgia, Athens, Georgia.ORCID 0000-0002-5471-1591
Michael AmlungFrom the, Peter Boris Centre for Addictions Research, (MM, MA, CM, JMa), St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada.
Ashley DennhardtDepartment of Psychology, (AD, JMu), University of Memphis, Memphis, Tennessee.
Mark FerroSchool of Public and Health Systems, (MF), University of Waterloo, Waterloo, ON, Canada.
Jillian HalladayOfford Centre for Child Studies, (JH), McMaster University, Hamilton, ON, Canada.
Catharine MunnFrom the, Peter Boris Centre for Addictions Research, (MM, MA, CM, JMa), St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada.
Jalie TuckerDepartment of Health Education & Behavior, (JT), Center for Behavioral Economic Health Research, University of Florida, Gainsville, Florida.ORCID 0000-0003-1055-9038
James MurphyDepartment of Psychology, (AD, JMu), University of Memphis, Memphis, Tennessee.
James MacKillopFrom the, Peter Boris Centre for Addictions Research, (MM, MA, CM, JMa), St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-8695-1071
St. Joseph’s Healthcare Hamilton · CAUniversity of Memphis · USMcMaster University Medical Centre · CAUniversity of Florida Health · USUniversity of Georgia · USUniversity of Kansas · USUniversity of Waterloo · CA

Funding

The role of religiosity, socioeconomic status and the relationship between behavioral economic variables as mediators of negative alcohol-related consequences in African American emerging adultsR01AA024930 · NIAAA · UNIVERSITY OF MEMPHIS · PI MACKILLOP, JAMES, MURPHY, JAMES G. · 2017 to 2021
$1.6M
CIHR 365297NIAAA NIH HHS R01 AA024930
6 · The paper itself

Abstract

backgroundHeavy episodic drinking (HED) is a major public health problem among emerging adults (individuals 18 to 25), but with considerable heterogeneity in concurrent substance use and psychopathology. The current study used latent profile analysis (LPA) to detect discrete subgroups of HED based on alcohol, other drug severity, and concurrent psychopathology. A reinforcer pathology approach was used to understand motivational differences among the latent subgroups.

methodsParticipants were 2 samples of emerging adults reporting regular HED, 1 Canadian (n = 730) and 1 American (n = 602). Indicators for the LPA were validated dimensional self-report assessments of alcohol severity, cannabis severity, other drug severity, nicotine dependence, depression, anxiety, posttraumatic stress disorder, and attention-deficit/hyperactivity disorder. Reinforcer pathology indicators were measures of alcohol demand, proportionate substance-related reinforcement, and discounting of future rewards.

resultsThe LPA yielded parallel 3-class solutions in both samples. The largest subgroup was characterized by comparatively low substance severity and psychopathology (Low overall severity). The second largest subgroup was characterized by comparatively high alcohol and other drug severity (excluding tobacco) and high levels of psychopathology (Heavy alcohol & high psychiatric severity). The third subgroup exhibited high alcohol, smoking and intermediate levels of other substance use and psychopathology (Heavy alcohol, smoking, & intermediate psychiatric severity). The Heavy alcohol & high psychiatric severity and Heavy alcohol, smoking, & intermediate psychiatric severity subgroups exhibited significantly higher alcohol demand, greater proportionate substance-related reinforcement, and steeper delay discounting.

conclusionsParallel latent subgroups of emerging adults engaging in HED were present in both samples, and the high-risk subgroups were significantly differentiated by the reinforcer pathology indicators. These latent profiles may ultimately inform heterogeneity in the longitudinal course of HED in emerging adults.

Indexed as

Reinforcement, PsychologyBinge DrinkingFemaleHumansMaleOntarioPsychiatric Status Rating ScalesPsychological TestsPsychopathologyRisk FactorsSubstance-Related DisordersSurveys and QuestionnairesTennesseeYoung AdultAlcoholBehavioral EconomicsEmerging AdultsLatent Profile AnalysisReinforcer Pathology

Identifiers

PMID32965723
PMCPMC7841846
OpenAlexW3088928894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.