ReviewCellular and molecular life sciences : CMLS2021
Diversity of intrinsically photosensitive retinal ganglion cells: circuits and functions.
Review in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 170 citations in OpenAlex.
- Trial
- SEX-DEPENDENT MODULATION OF WHOLE BRAIN cFOS EXPRESSION BY LIGHT AND MELANOPSIN IN THE MOUSE.bioRxiv : the preprint server for biology · 2026Article
- A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light-Sensitive R-Opsin.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The Diverse Role of ipRGCs in Visual Perception Beyond Non-Image-Forming Functions.The European journal of neuroscience · 2026Review
- Melanopic equivalent daylight illuminance of 2 lx maintains and restores physiological and neurophysiological circadian rhythms in rats.Scientific reports · 2026Article
- A hypothetical circadian‒endocrine pathway linking melanopsin-expressing ipRGC dysfunction in autoimmune retinopathy to sexual dysfunction.International ophthalmology · 2026Review
- Light tunes long-term threat avoidance behavior in male mice.Nature communications · 2026Article
- Expression atlas of Dmrt genes across sex and development in the mouse brain: functional insights from the olfactory system.Biology of sex differences · 2026Article
- The Effect of Optic Nerve Crush on Lens-Induced Myopia in Mice.Ophthalmology science · 2026Article
- Neuropsin-expressing cells in the retina affect melanopsin expression and response to light in mice.Scientific reports · 2026Article
- Stem Cell-Based Interventions for Retinal Ganglion Cell Protection and Regeneration in Glaucoma: A Review of Current Evidence and Future Directions.Ophthalmic research · 2026Review
- Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review).Molecular medicine reports · 2026Review
- Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and calcitonin gene-related peptide sensitization.Headache · 2026Article
- A lateral hypothalamic region supporting diverse visual processing and modulation of visually-guided behaviour.Nature communications · 2025Article
- Article
- Genetic tuning of retinal ganglion cell subtype identity to drive visual behavior.Nature communications · 2025Article
- Article
- Disrupted circadian rhythms and opioid-mediated adverse effects: Bidirectional relationship and putative mechanisms.Journal of neuroendocrinology · 2025Review
- On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025Review
- Brain circadian clocks timing the 24h rhythms of behavior.Npj biological timing and sleep · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are a relatively recently discovered class of atypical ganglion cell photoreceptor. These ipRGCs are a morphologically and physiologically heterogeneous population that project widely throughout the brain and mediate a wide array of visual functions ranging from photoentrainment of our circadian rhythms, to driving the pupillary light reflex to improve visual function, to modulating our mood, alertness, learning, sleep/wakefulness, regulation of body temperature, and even our visual perception. The presence of melanopsin as a unique molecular signature of ipRGCs has allowed for the development of a vast array of molecular and genetic tools to study ipRGC circuits. Given the emerging complexity of this system, this review will provide an overview of the genetic tools and methods used to study ipRGCs, how these tools have been used to dissect their role in a variety of visual circuits and behaviors in mice, and identify important directions for future study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.