Evidence map›Paper›PMID 32964759›Full record

ArticleJournal of the American Heart Association2020

Formation of Calcified Nodule as a Cause of Early In-Stent Restenosis in Patients Undergoing Dialysis.

Norihito Nakamura, Sho Torii, Hiroko Tsuchiya, Akihiko Nakano, Yuji Oikawa, Junji Yajima, Shigeru Nakamura, Masataka Nakano, Naoki Masuda, Hiroshi Ohta and 5 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Ostial right coronary artery lesions: what to know and how to overcome.Cardiovascular intervention and therapeutics · 2026
    Review
  4. Review
  5. Article
  6. Restenosis patterns after percutaneous coronary intervention with drug-coated balloons for de novo coronary lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  7. Review
  8. Article
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  16. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Norihito NakamuraDepartment of Cardiology Tokai University School of Medicine Kanagawa Japan.
Sho ToriiDepartment of Cardiology Tokai University School of Medicine Kanagawa Japan.
Hiroko TsuchiyaDepartment of Cardiology Gunma-ken Saiseikai-Maebashi Hospital Gunma Japan.
Akihiko NakanoDepartment of Cardiology Gunma-ken Saiseikai-Maebashi Hospital Gunma Japan.
Yuji OikawaDepartment of Cardiovascular Medicine The Cardiovascular Institute Tokyo Japan.
Junji YajimaDepartment of Cardiovascular Medicine The Cardiovascular Institute Tokyo Japan.
Shigeru NakamuraCardiovascular Center Kyoto-Katsura Hospital Kyoto Japan.
Masataka NakanoDepartment of Cardiology Ageo Chuo Medical Center Saitama Japan.
Naoki MasudaDepartment of Cardiology Ageo Chuo Medical Center Saitama Japan.
Hiroshi OhtaDepartment of Cardiology Itabashi Chuo Medical Center Tokyo Japan.
Kazuhiko YumotoDepartment of Cardiology Yokohama Rosai Hospital Kanagawa Japan.
Makoto NatsumedaDepartment of Cardiology Tokai University School of Medicine Kanagawa Japan.
Takeshi IjichiDepartment of Cardiology Tokai University School of Medicine Kanagawa Japan.
Yuji IkariDepartment of Cardiology Tokai University School of Medicine Kanagawa Japan.
Gaku NakazawaDepartment of Cardiology Kindai University Osaka Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Dialysis is an independent risk factor for in-stent restenosis (ISR) after stent implantation in coronary arteries. However, the characteristics of ISR in patients undergoing dialysis remain unclear, as there are no histological studies evaluating the causes of this condition. The aim of the present study was to investigate the causes of ISR between patients who are undergoing dialysis and those who are not by evaluating tissues obtained from ISR lesions using directional coronary atherectomy. Methods and Results A total of 29 ISR lesions from 29 patients included in a multicenter directional coronary atherectomy registry of 128 patients were selected for analysis and divided into a dialysis group (n=8) and a nondialysis group (n=21). Histopathological evaluation demonstrated that an in-stent calcified nodule was a major histological characteristic of ISR lesions in the dialysis group and the prevalence of an in-stent calcified nodule was significantly higher in the dialysis group compared with the nondialysis group (75% versus 5%, respectively;

Indexed as

Atherectomy, CoronaryCalcinosisCoronary RestenosisCoronary VesselsPercutaneous Coronary InterventionRenal DialysisAgedCoronary AngiographyDrug-Eluting StentsFemaleHumansMaleOutcome and Process Assessment, Health CareRegistriesRisk AssessmentRisk Factorscalcified noduledialysisdirectional coronary atherectomyin‐stent restenosis

Identifiers

PMID32964759
PMCPMC7792410

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.