Evidence map›Paper›PMID 32964478›Full record

ArticleLetters in applied microbiology2020

Efficacy of alcohol-based hand sanitizers against human norovirus using RNase-RT-qPCR with validation by human intestinal enteroid replication.

B I Escudero-Abarca, R M Goulter, J W Arbogast, R A Leslie, K Green, L-A Jaykus

Abstract read
In one paragraph

Article in Letters in applied microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

B I Escudero-AbarcaDepartment of Food Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA.
R M GoulterDepartment of Food Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0002-7302-5044
J W ArbogastGOJO Industries Inc, Akron, OH, USA.
R A LeslieGOJO Industries Inc, Akron, OH, USA.
K GreenGOJO Industries Inc, Akron, OH, USA.
L-A JaykusDepartment of Food Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA.

Funding

GOJO Industries, Inc.
6 · The paper itself

Abstract

Successful human norovirus (HuNoV) cultivation in stem cell-derived human intestinal enteroids (HIE) was recently reported. The purpose of this study was to evaluate the anti-HuNoV efficacy of two alcohol-based commercial hand sanitizers and 60% ethanol by suspension assay using RNase-RT-qPCR, with subsequent validation of efficacy by HuNoV cultivation using the HIE model. In suspension, when evaluated by RNase-RT-qPCR, 60% ethanol resulted in less than one log

Indexed as

Caliciviridae InfectionsDrug Evaluation, PreclinicalEthanolHand SanitizersHumansIntestinesNorovirusReal-Time Polymerase Chain ReactionRibonucleasesVirus ReplicationEthanolHand SanitizersRibonucleasesdisinfectionfood safetyhuman intestinal enteroidshuman norovirusRT-qPCR

Identifiers

PMID32964478
PMCPMC7756425

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.